Evidence map›Paper›PMID 33996074›Full record

ReviewTherapeutic advances in infectious disease

Antimicrobial stewardship and antibiograms: importance of moving beyond traditional antibiograms.

Kenneth P Klinker, Levita K Hidayat, C Andrew DeRyke, Daryl D DePestel, Mary Motyl, Karri A Bauer

Registry-linked trialAbstract readReview
In one paragraph

Review in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05239312 (Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital), which is not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05239312 unknown statusnot on this map

Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital

TypeobservationalSponsorAssiut UniversityRan2022 to 2024Enrolled90ConditionsProsthetic Joint InfectionArmsAntimicrobial
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. An analysis of the value-added of antibiogram subgroup stratification.Annals of clinical microbiology and antimicrobials · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kenneth P KlinkerMRL, Merck & Co., Inc., Kenilworth, NJ, USA.
Levita K HidayatMRL, Merck & Co., Inc., Kenilworth, NJ, USA.
C Andrew DeRykeMRL, Merck & Co., Inc., Kenilworth, NJ, USA.
Daryl D DePestelMRL, Merck & Co., Inc., Kenilworth, NJ, USA.
Mary MotylMRL, Merck & Co., Inc., Kenilworth, NJ, USA.
Karri A BauerMRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA.ORCID https://orcid.org/0000-0003-1219-8133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid evolution of resistance, particularly among Gram-negative bacteria, requires appropriate identification of patients at risk followed by administration of appropriate empiric antibiotic therapy. A primary tenet of antimicrobial stewardship programs (ASPs) is the establishment of empiric antibiotic recommendations for commonly encountered infections. An important tool in providing empiric antibiotic therapy recommendations is the use of an antibiogram. While the majority of institutions use a traditional antibiogram, ASPs have an opportunity to enhance antibiogram data. The authors provide the rationale for why ASPs should implement alternative antibiograms, and the importance of incorporating an antibiogram into clinical decision support systems with the goal of providing effective empiric antibiotic therapy.

Indexed as

antibiogramAntimicrobial stewardshipantimicrobial stewardship program

Identifiers

PMID33996074
PMCPMC8111534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.