Evidence map›Paper›PMID 33996058›Full record

ReviewAnnals of medicine and surgery (2012)2021

Plexus anesthesia versus general anesthesia for carotid endarterectomy: A systematic review with meta-analyses.

M S Marsman, J Wetterslev, F Keus, D van Aalst, F G van Rooij, J M M Heyligers, F L Moll, A Kh Jahrome, P W H E Vriens, G G Koning

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

M S MarsmanDepartment of Vascular Surgery, Rijnstate Hospital, Arnhem, the Netherlands.
J WetterslevCopenhagen Trial Unit, Center for Clinical Intervention Research, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark.
F KeusDepartment of Critical Care, University of Groningen, University Medical Center Groningen, the Netherlands.
D van AalstDepartment of Anesthesiology, Radboud University Medical Center Nijmegen, Nijmegen, the Netherlands.
F G van RooijDepartment of Neurology, Medical Center Leeuwarden, Leeuwarden, the Netherlands.
J M M HeyligersDepartment of Vascular Surgery, Elisabeth-TweeSteden Hospital, Tilburg, the Netherlands.
F L MollDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
A Kh JahromeDepartment of Vascular Surgery, Medical Center Leeuwarden, Leeuwarden, the Netherlands.
P W H E VriensDepartment of Vascular Surgery, Elisabeth-TweeSteden Hospital, Tilburg, the Netherlands.
G G KoningDepartment of Vascular Surgery, ZGT, Hospital Group Twente, Almelo/Hengelo, the Netherlands.
Elisabeth-TweeSteden Ziekenhuis · NLMedisch Centrum Leeuwarden · NLCopenhagen University Hospital · DKRadboud University Medical Center · NLRijnstate Hospital · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NLZiekenhuis Groep Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTraditional carotid endarterectomy is considered to be the standard technique for prevention of a new stroke in patients with a symptomatic carotid stenosis. Use of plexus anesthesia or general anesthesia in traditional carotid endarterectomy is, to date, not unequivocally proven to be superior to one other. A systematic review was needed for evaluation of benefits and harms to determine which technique, plexus anesthesia or general anesthesia is more effective for traditional carotid endarterectomy in patients with symptomatic carotid stenosis.

methodsThe review was conducted according to our protocol following the recommendations of Cochrane and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Searches were updated on the October 1, 2020. We did not find any randomized clinical trial comparing plexus anesthesia and general anesthesia in carotid endarterectomy with patch angioplasty matching our protocol criteria in patients with a symptomatic and significant (≥50%) carotid stenosis.

conclusionsBased on the current, high risk of bias evidence, we concluded there is a need for new randomized clinical trials with overall low risk of bias comparing plexus anesthesia with general anesthesia in carotid endarterectomy with patch closure of the arterial wall in patients with a symptomatic and significant (≥50%) stenosis of the internal carotid artery.Protocol unique identification number (UIN): CRD42019139913, (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=139913).

Indexed as

Carotid endarterectomyGeneralLocal anesthesiaPlexusStenosisSystematic review

Identifiers

PMID33996058
PMCPMC8094902
OpenAlexW3154400296

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.