ArticleObstetric medicine2021
Utility of erythrocyte indices in identifying iron depletion in pregnancy.
Article in Obstetric medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Clinical utility of calculated haematological parameters in the diagnosis of iron deficiency anaemia in pregnant women.Biomedical reports · 2025Article
- Red blood cell indices versus serum ferritin as surrogate markers of iron deficiency during pregnancy.PloS one · 2025Article
- Diagnostic Accuracy of Hemoglobin Levels and Red Blood Cell Parameters for Iron Deficiency in Adolescents: A Cross-Sectional Study.Global pediatric health · 2024Article
- Lactate Production can Function to Increase Human Epithelial Cell Iron Concentration.Cellular and molecular bioengineering · 2022Article
- Diagnostic value of reticulocyte indices for the assessment of the iron status of cats with chronic kidney disease.Journal of veterinary internal medicine · 2022Article
- Iron deficiency anaemia in pregnancy: A contemporary review.Obstetric medicine · 2021Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIron deficiency anaemia in pregnancy is common and is a major cause of maternal and neonatal morbidity worldwide. Serum ferritin is the current gold standard test for identifying iron depletion, with a cut-off value of 30 µg/L. Recent studies in low- and middle-income countries have identified mean cell haemoglobin concentration as a surrogate marker for the prediction of iron depletion.
methodsWe studied values from 786 antenatal blood results from 2018 in Oxford, UK, and correlated the red cell indices with serum ferritin measurements.
resultsHaemoglobin, mean cell volume, mean cell haemoglobin and mean cell haemoglobin concentration have low specificity and sensitivity for the identification of iron depletion.
conclusionsWe found that haemoglobin, mean cell volume, mean cell haemoglobin and mean cell haemoglobin concentration do not have sufficient predictive value in this population to be used as a screening test for non-anaemic iron depletion.
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