Evidence map›Paper›PMID 33995532›Full record

ArticleInternational journal of pediatrics2021

Comparative Study of Chikungunya Only and Chikungunya-Scrub Typhus Coinfection in Children: Findings from a Hospital-Based Observational Study from Central Nepal.

Santosh Pathak, Nagendra Chaudhary, Prativa Dhakal, Sanjay Ray Yadav, Binod Kumar Gupta, Om Prakash Kurmi

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Article in International journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Scrub Typhus and Influenza A Co-Infection: A Case Report.Pathogens (Basel, Switzerland) · 2025
    Article
  5. Molecular and serological evidence of chikungunya virus infection with high case fatality among pediatric population with acute encephalitis syndrome: first report from Eastern Uttar Pradesh, India.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  6. Extra-articular Manifestations of Chikungunya.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Santosh PathakDepartment of Pediatrics, Chitwan Medical College, Bharatpur, Nepal.ORCID https://orcid.org/0000-0002-1500-3154
Nagendra ChaudharyDepartment of Pediatrics, Universal College of Medical Sciences, Bhairahawa, Nepal.ORCID https://orcid.org/0000-0002-3216-8671
Prativa DhakalDepartment of Nursing, Chitwan Medical College, Bharatpur, Nepal.
Sanjay Ray YadavDepartment of Biochemistry, Chitwan Medical College, Bharatpur, Nepal.
Binod Kumar GuptaDepartment of Pediatrics, Universal College of Medical Sciences, Bhairahawa, Nepal.ORCID https://orcid.org/0000-0001-9606-5367
Om Prakash KurmiCentre for Population Health Research, Bhairahawa, Nepal.ORCID https://orcid.org/0000-0002-9518-4716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesChikungunya and scrub typhus infection are important causes of undifferentiated fever in tropical zones. The clinical manifestations in both conditions are nonspecific and often overlap. This study compares the clinical manifestations and the outcome of chikungunya with chikungunya-scrub typhus coinfection in children.

methodsA hospital-based observational study was conducted in children below 15 years of age over 16-month duration in 2017-2018. Chikungunya was diagnosed by IgM ELISA. All positive chikungunya cases were subjected to scrub typhus testing, dengue testing, leptospira testing, and malaria testing. Clinical manifestations and outcomes of all patients were recorded.

resultsOut of the 382 admitted cases with fever, 11% (

conclusionsBoth the chikungunya and scrub typhus coinfection groups shared many similar clinical manifestations. In children, coinfection with scrub typhus often leads to modification of the clinical profile, complications, and chikungunya outcome.

Identifiers

PMID33995532
PMCPMC8081591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.