ArticleFrontiers in immunology2021
Role of Tonsillar Chronic Inflammation and Commensal Bacteria in the Pathogenesis of Pediatric OSA.
Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Altered Tonsillar Microbiome in Children with Down Syndrome and Obstructive Sleep Apnea.bioRxiv : the preprint server for biology · 2026Article
- Protocol for generating human tonsil immune organoids with epithelial and germinal center layers using low-Matrigel culture.STAR protocols · 2026Article
- Adenotonsillar Microbiome Shifts in Children With Obstructive Sleep Apnea Syndrome.The Laryngoscope · 2026Article
- Surgical removal of Waldeyer's ring and long-term risk of Sjögren's syndrome: a population-based cohort study investigating the mucosal immune link.Frontiers in immunology · 2026Article
- T cells in Group AFrontiers in cellular and infection microbiology · 2026Review
- Risk factors of sleep-disordered breathing and poor asthma control in children with asthma.BMC pediatrics · 2024Article
- Role of germinal center and CD39Immunity & ageing : I & A · 2024Article
- Vitamin D Deficit as Inducer of Adenotonsillar Hypertrophy in Children with Obstructive Sleep Apnea-A Prospective Case-Control Study.Children (Basel, Switzerland) · 2023Article
- Changes in the oral and nasal microbiota in pediatric obstructive sleep apnea.Journal of oral microbiology · 2023Article
- Pediatric sleep apnea and viral respiratory infections: what do clinicians need to know?Expert review of respiratory medicine · 2022Article
- Characteristics of the bacterial microbiota in the upper respiratory tract of children.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Characteristics of salivary microbiota in children with obstructive sleep apnea: A prospective study with polysomnography.Frontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune responses at the boundary between the host and the world beyond are complex and mucosal tissue homeostasis relies on them. Obstructive sleep apnea (OSA) is a syndrome suffered by children with hypertrophied tonsils. We have previously demonstrated that these tonsils present a defective regulatory B cell (Breg) compartment. Here, we extend those findings by uncovering the crucial role of resident pro-inflammatory B and T cells in sustaining tonsillar hypertrophy and hyperplasia by producing TNFα and IL17, respectively, in
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Registered trials
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