Evidence map›Paper›PMID 33995356›Full record

ReviewFrontiers in immunology2021

The Importance of Glycans of Viral and Host Proteins in Enveloped Virus Infection.

Yuqing Li, Dongqi Liu, Yating Wang, Wenquan Su, Gang Liu, Weijie Dong

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 135 citations in OpenAlex.

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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuqing LiDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, China.
Dongqi LiuThe Queen's University of Belfast Joint College, China Medical University, Shenyang, China.
Yating WangDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, China.
Wenquan SuDalian Medical University, Dalian, China.
Gang LiuDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, China.
Weijie DongDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, China.
Dalian Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal viruses are parasites of animal cells that have characteristics such as heredity and replication. Viruses can be divided into non-enveloped and enveloped viruses if a lipid bilayer membrane surrounds them or not. All the membrane proteins of enveloped viruses that function in attachment to target cells or membrane fusion are modified by glycosylation. Glycosylation is one of the most common post-translational modifications of proteins and plays an important role in many biological behaviors, such as protein folding and stabilization, virus attachment to target cell receptors and inhibition of antibody neutralization. Glycans of the host receptors can also regulate the attachment of the viruses and then influence the virus entry. With the development of glycosylation research technology, the research and development of novel virus vaccines and antiviral drugs based on glycan have received increasing attention. Here, we review the effects of host glycans and viral proteins on biological behaviors of viruses, and the opportunities for prevention and treatment of viral infectious diseases.

Indexed as

VirusesVirus InternalizationAnimalsGlycosylationHost-Parasite InteractionsHumansImmune EvasionPolysaccharidesReceptors, VirusPolysaccharidesReceptors, Virusenveloped virusglycanhostimmune escapevaccine

Identifiers

PMID33995356
PMCPMC8116741
OpenAlexW3158336232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.