Evidence map›Paper›PMID 33995317›Full record

ArticleFrontiers in microbiology2021

Samantha Knott, Dylan Curry, Neil Zhao, Pallavi Metgud, Sana S Dastgheyb, Caroline Purtill, Marc Harwood, Antonia F Chen, Thomas P Schaer, Michael Otto and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Methicillin-resistantAntimicrobial agents and chemotherapy · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Simulated Media for Mimicking the Human Environment In Vitro.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Review
  11. Review
  12. The endothelium at the interface between tissues andClinical microbiology reviews · 2025
    Review
  13. Review
  14. Resveratrol inhibits the formation ofFrontiers in veterinary science · 2025
    Article
  15. Article
  16. What Is a Biofilm? Lessons Learned from Interactions with Immune Cells.International journal of molecular sciences · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Samantha KnottDepartment of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, United States.
Dylan CurryDepartment of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, United States.
Neil ZhaoDepartment of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, United States.
Pallavi MetgudDepartment of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, United States.
Sana S DastgheybDepartment of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, United States.
Caroline PurtillDepartment of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, United States.
Marc HarwoodRothman Orthopaedic Institute, Philadelphia, PA, United States.
Antonia F ChenDepartment of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, PA, United States.
Thomas P SchaerDepartment of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, United States.
Michael OttoPathogen Molecular Genetics Section, Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Noreen J HickokDepartment of Orthopaedic Surgery, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, United States.
Thomas Jefferson University · USBrigham and Women's Hospital · USNational Institutes of Health · USRothman Orthopaedics · USUniversity of Pennsylvania · US

Funding

Role of the human microbiota and probioticsZIAAI001080 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI OTTO, MICHAEL · 2009 to 2025
$9.7M
Plasma-based therapies for bone infection: A tripartite USA/Northern Ireland/Republic of Ireland consortiumR01AR076941 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI BOURKE, PAULA, FREEMAN, THERESA A · 2020 to 2025
$3.3M
Preventing Spinal Infection: Ultrasound Triggered ProphylaxisR01AR069119 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI Flemming Forsberg, Noreen J Hickok · 2016 to 2026
$3.2M
Synovial Fluid and Joint SepsisR01AR072513 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI HICKOK, NOREEN J · 2017 to 2021
$2.5M
Intramural NIH HHS ZIA AI001080NIAMS NIH HHS R01 AR069119NIAMS NIH HHS R01 AR072513NIAMS NIH HHS R01 AR076941
6 · The paper itself

Abstract

Biofilms are typically studied in bacterial media that allow the study of important properties such as bacterial growth. However, the results obtained in such media cannot take into account the bacterial localization/clustering caused by bacteria-protein interactions

Indexed as

antibiotic tolerancebiofilmStaphylococcus aureussynovial fluidvirulence factors

Identifiers

PMID33995317
PMCPMC8117011
OpenAlexW3158869156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.