Evidence map›Paper›PMID 33995124›Full record

ReviewFrontiers in physiology2021

Bioactive Compounds in Edible Oils and Their Role in Oxidative Stress and Inflammation.

Alessandra Mazzocchi, Valentina De Cosmi, Patrizia Risé, Gregorio Paolo Milani, Stefano Turolo, Marie-Louise Syrén, Angelo Sala, Carlo Agostoni

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 79 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Analysis of Quality Distinctions of Pumpkin Seed Oil (Molecules (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Hydroethanolic Extract ofPlants (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alessandra MazzocchiDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Valentina De CosmiDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Patrizia RiséDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Gregorio Paolo MilaniDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Stefano TuroloPediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Marie-Louise SyrénDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Angelo SalaDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Carlo AgostoniDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITInstitute for Biomedical Research and Innovation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diet and inflammatory response are recognized as strictly related, and interest in exploring the potential of edible fats and oils for health and chronic diseases is emerging worldwide. Polyunsaturated fatty acids (PUFAs) present in fish oil (FO), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may be partly converted into oxygenated bioactive lipids with anti-inflammatory and/or pro-resolving activities. Moreover, the co-presence of phenolic compounds and vitamins in edible oils may prevent the development of chronic diseases by their anti-inflammatory, antioxidant, neuroprotective, and immunomodulatory activities. Finally, a high content in mono-unsaturated fatty acids may improve the serum lipid profile and decrease the alterations caused by the oxidized low-density lipoproteins and free radicals. The present review aims to highlight the role of lipids and other bioactive compounds contained in edible oils on oxidative stress and inflammation, focusing on critical and controversial issues that recently emerged, and pointing to the opposing role often played by edible oils components and their oxidized metabolites.

Indexed as

alpha-linolenic aciddocosahexaenoic acidedible oilimmune responseinflammation resolutionlinoleic acidmarine oilvegetable oil

Identifiers

PMID33995124
PMCPMC8119658
OpenAlexW3159424786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.