Evidence map›Paper›PMID 33995087›Full record

ArticleFrontiers in pharmacology2021

Xiaokang Wang, Chunxiao Ye, Tianrong Xun, Liqian Mo, Yong Tong, Wensi Ni, Suping Huang, Bin Liu, Xia Zhan, Xixiao Yang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 27 citations in OpenAlex.

  1. NontoxigenicMicroorganisms · 2026
    Review
  2. Review
  3. Review
  4. Microbial Biotransformation of Chicory byInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Journal of clinical and translational hepatology · 2024
    Article
  17. Review
  18. Article
  19. Review
  20. Regulation ofFrontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Xiaokang WangDepartment of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Chunxiao YeDepartment of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Tianrong XunDepartment of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Liqian MoDepartment of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yong TongDepartment of Hematology, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Wensi NiDepartment of Pediatric, Shenzhen University General Hospital, Shenzhen, China.
Suping HuangDepartment of Intensive Care Unit, Shenzhen Longhua District Central Hospital, Shenzhen, China.
Bin LiuDepartment of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Xia ZhanDepartment of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Xixiao YangDepartment of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Southern Medical University · CNSouthern Medical University Shenzhen Hospital · CNLonggang Central Hospital · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antifungal agent voriconazole (VRC) exhibits extreme inter-individual and intra-individual variation in terms of its clinical efficacy and toxicity. Inflammation, as reflected by C-reactive protein (CRP) concentrations, significantly affects the metabolic ratio and trough concentrations of voriconazole.

Indexed as

abnormal metabolismhepatic inflammationpolysaccharide ATLR4 (toll-like receptor 4)voriconazole

Identifiers

PMID33995087
PMCPMC8115215
OpenAlexW3155982173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.