ArticleFrontiers in neuroscience2021
Longer and Deeper Desaturations Are Associated With the Worsening of Mild Sleep Apnea: The Sleep Heart Health Study.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Polysomnographic phenotypes: predictors of treatment response in Obstructive Sleep Apnea with Mandibular Advancement devices.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Trial
- Three-class obstructive sleep apnea severity assessment: a parallel AHI and ODI explainable artificial intelligence framework using craniofacial-enriched clinical data.Sleep & breathing = Schlaf & Atmung · 2026Article
- Prevalence and predictors of obstructive sleep apnea in collegiate football players.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Cerebrovascular pathology mediates associations between hypoxemia during rapid eye movement sleep and medial temporal lobe structure and function in older adults.bioRxiv : the preprint server for biology · 2024Article
- A Review of Novel Oximetry Parameters for the Prediction of Cardiovascular Disease in Obstructive Sleep Apnoea.Diagnostics (Basel, Switzerland) · 2023Review
- Prediction of the Sleep Apnea Severity Using 2D-Convolutional Neural Networks and Respiratory Effort Signals.Diagnostics (Basel, Switzerland) · 2023Article
- Utilizing Envelope Analysis of a Nasal Pressure Signal for Sleep Apnea Severity Estimation.Diagnostics (Basel, Switzerland) · 2023Article
- Mitochondria Need Their Sleep: Redox, Bioenergetics, and Temperature Regulation of Circadian Rhythms and the Role of Cysteine-Mediated Redox Signaling, Uncoupling Proteins, and Substrate Cycles.Antioxidants (Basel, Switzerland) · 2023Article
- A novel OSA-related model of intermittent hypoxia in endothelial cells under flow reveals pronounced inflammatory pathway activation.Frontiers in physiology · 2023Article
- Diabetes and cardiovascular diseases are associated with the worsening of intermittent hypoxaemia.Journal of sleep research · 2022Article
- Associations of sleep apnea risk and oxygen desaturation indices with cerebral small vessel disease burden in patients with stroke.Frontiers in neurology · 2022Article
- Pediatric Sleep Apnea: The Overnight Electroencephalogram as a Phenotypic Biomarker.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
STUDY
objectivesObesity, older age, and male sex are recognized risk factors for sleep apnea. However, it is unclear whether the severity of hypoxic burden, an essential feature of sleep apnea, is associated with the risk of sleep apnea worsening. Thus, we investigated our hypothesis that the worsening of sleep apnea is expedited in individuals with more severe desaturations.
methodsThe blood oxygen saturation (SpO
resultsIn the group consisting of both men and women, avg. DesDur (β = 1.594,
conclusionLonger and deeper desaturations are more likely to expose a patient to the worsening of sleep apnea. This information could be useful in the planning of follow-up monitoring or lifestyle counseling in the early stage of the disease.
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Registered trials
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