Evidence map›Paper›PMID 33994926›Full record

SynthesisFrontiers in neuroscience2021

Microbial Pathogenesis and Pathophysiology of Alzheimer's Disease: A Systematic Assessment of Microorganisms' Implications in the Neurodegenerative Disease.

Temitope Cyrus Ekundayo, Tosin Abiola Olasehinde, Kunle Okaiyeto, Anthony I Okoh

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Alzheimer's Disease: Significant Benefit from the Yeast-Based Models.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Temitope Cyrus EkundayoSAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice, South Africa.
Tosin Abiola OlasehindeSAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice, South Africa.
Kunle OkaiyetoSAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice, South Africa.
Anthony I OkohSAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice, South Africa.
University of Fort Hare · ZAFederal Institute of Industrial Research Oshodi · NGOndo State University of Science and Technology · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial infections have been linked to the pathogenesis and pathophysiology of Alzheimer's disease (AD) and other neurodegenerative diseases. The present study aimed to synthesise and assess global evidence of microbial pathogenesis and pathophysiology in AD (MPP-AD) and associated neurodegenerative conditions using integrated science mapping and content analytics to explore the associated research landscape. Relevant MPP-AD documents were retrieved from Web of Science and Scopus according to PRISMA principles and analysed for productivity/trend linked to authors/countries, thematic conceptual framework, and international collaborative networks. A total of 258 documents published from 136 sources to 39.42 average citations/document were obtained on MPP-AD. The co-authors per document were 7.6, and the collaboration index was 5.71. The annual research outputs increased tremendously in the last 6 years from 2014 to 2019, accounting for 66% compared with records in the early years from 1982 to 1990 (16%). The USA (

Indexed as

Alzheimer's diseasegut microbiotamicrobial pathogenesisneurodegenerative diseasepathophysiologyyeast model

Identifiers

PMID33994926
PMCPMC8113417
OpenAlexW3157263362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.