Evidence map›Paper›PMID 33994860›Full record

SynthesisInternational journal of biological sciences2021

Long Noncoding RNA KCNQ1OT1 is a Prognostic Biomarker and mediates CD8

Zheng-Bin Lin, Pei Long, Zhan Zhao, Yi-Ran Zhang, Xiao-Dong Chu, Xiao-Xu Zhao, Hui Ding, Song-Wei Huan, Yun-Long Pan, Jing-Hua Pan

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  7. Review
  8. Review
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  10. Review
  11. Prioritizing context-specific genetic risk mechanisms in 11 solid cancers.medRxiv : the preprint server for health sciences · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Epigenomics · 2024
    Article
  16. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zheng-Bin LinDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Pei LongCollege of Pharmacy, Jinan University, Guangzhou, 510632, China.
Zhan ZhaoDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Yi-Ran ZhangDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Xiao-Dong ChuDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Xiao-Xu ZhaoDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Hui DingDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Song-Wei HuanDepartment of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Yun-Long PanDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Jing-Hua PanDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
First Affiliated Hospital of Jinan University · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, NeoplasticApoptosisCD8-Positive T-LymphocytesCell MovementCell ProliferationColorectal NeoplasmsHumansPotassium Channels, Voltage-GatedTumor Cells, CulturedKCNQ1OT1 long non-coding RNA, humanPotassium Channels, Voltage-GatedbioinformaticscancerlncRNA KCNQ1OT1prognosisT cell exhaustiontumor-infiltrating

Identifiers

PMID33994860
PMCPMC8120463
OpenAlexW3159607105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.