Evidence map›Paper›PMID 33994706›Full record

ReviewJournal of orthopaedics

Ultra-high molecular weight polyethylene (UHMWPE) for hip and knee arthroplasty: The present and the future.

Alessandro Bistolfi, Fortunato Giustra, Francesco Bosco, Luigi Sabatini, Alessandro Aprato, Pierangiola Bracco, Anuj Bellare

Abstract readReview
In one paragraph

Review in Journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. Future Frontiers in Bioinspired Implanted Biomaterials.Advanced materials (Deerfield Beach, Fla.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessandro BistolfiDepartment of Orthopaedics, Traumatology and Rehabilitation, C.T.O. Hospital. AOU Città della Salute e della Scienza, Via Zuretti 29, 10126, Turin, Italy.
Fortunato GiustraDepartment of Orthopaedics, Traumatology and Rehabilitation, C.T.O. Hospital. AOU Città della Salute e della Scienza, Via Zuretti 29, 10126, Turin, Italy.
Francesco BoscoDepartment of Orthopaedics, Traumatology and Rehabilitation, C.T.O. Hospital. AOU Città della Salute e della Scienza, Via Zuretti 29, 10126, Turin, Italy.
Luigi SabatiniDepartment of Orthopaedics, Traumatology and Rehabilitation, C.T.O. Hospital. AOU Città della Salute e della Scienza, Via Zuretti 29, 10126, Turin, Italy.
Alessandro ApratoDepartment of Orthopaedics, Traumatology and Rehabilitation, C.T.O. Hospital. AOU Città della Salute e della Scienza, Via Zuretti 29, 10126, Turin, Italy.
Pierangiola BraccoDepartment of Chemistry and NIS (Nanostructured Interfaces and Surfaces) Center, University of Torino, 10125, Torino, Italy.
Anuj BellarePolymerix LLC, Boston, MA, 02134, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeto review advances and clinical performance of polyethylene in total joint arthroplasty, summing up historical problems and focusing on the latest innovations.

methodssearch for medical grade Ultra-High-Molecular-Weight-Polyethylene (UHMWPE); Data Sources: PubMed, Scopus, Cochrane Library.

resultsthe increasing number of joint arthroplasties and high-activity patients led to progressive developments of bearing surfaces to improve performance and durability. Different strategies such as crosslinking UHMWPE (HXLPE) and the addition of vitamin-E (HXLPE) have been tested to improve wear and oxidation resistance.

conclusionRecent innovations about UHMWPE showed improvements either for hip and knee, with the potential of long-term survivorship.

Indexed as

ArthroplastyCrosslinkingHipKneeMechanical propertiesPolyethyleneUHMWPEVitamin EWear

Identifiers

PMID33994706
PMCPMC8102204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.