Evidence map›Paper›PMID 33994657›Full record

ArticleJournal of carbohydrate chemistry2020

Synthesis of glycoimmunogen Tn-Thr-PS A1

F Hossain, S Nishat, S Ghosh, S Boga, G T Hymel, P R Andreana

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of carbohydrate chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

F HossainDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, OH 43606, USA.
S NishatDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, OH 43606, USA.
S GhoshDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, OH 43606, USA.
S BogaDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, OH 43606, USA.
G T HymelDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, OH 43606, USA.
P R AndreanaDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, OH 43606, USA.
University of Toledo · US

Funding

Entirely Carbohydrate Vaccine Constructs and Their Application in Probing GlycoimR01CA156661 · NCI · WAYNE STATE UNIVERSITY · PI ANDREANA, PETER R · 2011 to 2015
$1.7M
NCI NIH HHS R01 CA156661
6 · The paper itself

Abstract

Previously, our group constructed several immunogens utilizing oxime linkage to conjugate a T-cell stimulatory zwitterionic polysaccharide PS A1 and tumor associated carbohydrate antigens (TACAs) in acetate buffer. Here, a semi-synthetic immunogen was synthesized using hydrazone conjugation between PS A1 and a glycopeptide hydrazide (α-d-GalNAc-l-Thr-NH-NH

Indexed as

Carbohydrate-based immunogenhydrazone conjugationregioselective conjugationstability studyzwitterionic polysaccharide

Identifiers

PMID33994657
PMCPMC8118568
OpenAlexW3004611880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.