Evidence map›Paper›PMID 33994544›Full record

ArticleLight, science & applications2021

Isotropically resolved label-free tomographic imaging based on tomographic moulds for optical trapping.

Moosung Lee, Kyoohyun Kim, Jeonghun Oh, YongKeun Park

Open access · goldAbstract read
In one paragraph

Article in Light, science & applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  6. Three-dimensional isotropic imaging of live suspension cells enabled by droplet microvortices.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Optical single-pixel volumetric imaging by three-dimensional light-field illumination.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Moosung LeeDepartment of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, South Korea.
Kyoohyun KimDepartment of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, South Korea.
Jeonghun OhDepartment of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, South Korea.
YongKeun ParkDepartment of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, South Korea. yk.park@kaist.ac.kr.ORCID http://orcid.org/0000-0003-0528-6661
Korea Advanced Institute of Science and Technology · KR

Funding

National Research Foundation of Korea (NRF) 2015R1A3A2066550National Research Foundation of Korea (NRF) 2017M3C1A3013923National Research Foundation of Korea (NRF) 2018K000396
6 · The paper itself

Abstract

A major challenge in three-dimensional (3D) microscopy is to obtain accurate spatial information while simultaneously keeping the microscopic samples in their native states. In conventional 3D microscopy, axial resolution is inferior to spatial resolution due to the inaccessibility to side scattering signals. In this study, we demonstrate the isotropic microtomography of free-floating samples by optically rotating a sample. Contrary to previous approaches using optical tweezers with multiple foci which are only applicable to simple shapes, we exploited 3D structured light traps that can stably rotate freestanding complex-shaped microscopic specimens, and side scattering information is measured at various sample orientations to achieve isotropic resolution. The proposed method yields an isotropic resolution of 230 nm and captures structural details of colloidal multimers and live red blood cells, which are inaccessible using conventional tomographic microscopy. We envision that the proposed approach can be deployed for solving diverse imaging problems that are beyond the examples shown here.

Identifiers

PMID33994544
PMCPMC8126562
OpenAlexW3161719351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.