ArticleNucleic acids research1988
Codon preference in Dictyostelium discoideum.
Article in Nucleic acids research, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- repE--the Dictyostelium homolog of the human xeroderma pigmentosum group E gene is developmentally regulated and contains a leucine zipper motif.Nucleic acids research · 1996Article
- Functional expression of rat GLUT 1 glucose transporter in Dictyostelium discoideum.The Biochemical journal · 1996Article
- Analysis of gene function in Dictyostelium.Experientia · 1995Review
- Ponticulin is an atypical membrane protein.The Journal of cell biology · 1994Article
- Recent evidence for evolution of the genetic code.Microbiological reviews · 1992Review
- Essential factors determining codon usage in ubiquitin genes.Journal of molecular evolution · 1991Article
- Identification of a protein kinase multigene family of Dictyostelium discoideum: molecular cloning and expression of a cDNA encoding a developmentally regulated protein kinase.Proceedings of the National Academy of Sciences of the United States of America · 1991Article
- Developmentally regulated protein-tyrosine kinase genes in Dictyostelium discoideum.Molecular and cellular biology · 1990Article
- Two separable promoters control different aspects of expression of a Dictyostelium gene.Nucleic acids research · 1990Article
- Nucleotide sequences of Dictyostelium discoideum developmentally regulated cDNAs rich in (AAC) imply proteins that contain clusters of asparagine, glutamine, or threonine.Molecular & general genetics : MGG · 1989Article
- The Dictyostelium gelation factor shares a putative actin binding site with alpha-actinins and dystrophin and also has a rod domain containing six 100-residue motifs that appear to have a cross-beta conformation.The Journal of cell biology · 1989Article
- Codon usage and gene expression level in Dictyostelium discoideum: highly expressed genes do 'prefer' optimal codons.Nucleic acids research · 1989Article
- Complementation of a Dictyostelium discoideum thymidylate synthase mutation with the mouse gene provides a new selectable marker for transformation.Nucleic acids research · 1989Article
- Sequence organization and gene expression of pGD1, a plasmid found in a wild isolate of Dictyostelium.Nucleic acids research · 1989Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Dictyostelium discoideum is of increasing interest as a model eukaryotic cell because its many attributes have recently been expanded to include improved genetic and biochemical manipulability. The ability to transform Dictyostelium using drug resistance as a selectable marker (1) and to gene target by high frequency homologous integration (2) makes this organism particularly useful for molecular genetic approaches to cell structure and function. Given this background, it becomes important to analyze the codon preference used in this organism. Dictyostelium displays a strong and unique overall codon preference. This preference varies between different coding regions and even varies between coding regions from the same gene family. The degree of codon preference may be correlated with expression levels but not with the developmental time of expression of the gene product. The strong codon preference can be applied to identify coding regions in Dictyostelium DNA and aid in the design of oligonucleotide probes for cloning Dictyostelium genes.
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