ArticleJournal of sport and health science2021
Mediation role of cardiorespiratory fitness on the association between fatness and cardiometabolic risk in European adolescents: The HELENA study.
Article in Journal of sport and health science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 35 citations in OpenAlex.
- Ultrasound characteristics vs. outdoor activities impacts on obese adolescents: a cross-sectional cardiopulmonary study.Nutrition & metabolism · 2026Article
- Perinatal factors and their association with cardiometabolic profile in schoolchildren.Italian journal of pediatrics · 2026Article
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- Screen time and cardiorespiratory fitness in school-aged children: a sex-specific association independent of physical activity-evidence from Croatia.Frontiers in public health · 2026Article
- Dao Yin practice for student wellbeing: a classroom-based pilot study.Frontiers in psychology · 2026Article
- Trends in physical fitness among children and adolescents in Europe: A systematic review and meta-analyses during and after the COVID-19 pandemic.Journal of sport and health science · 2025Review
- Supervised Machine Learning Algorithms for Fitness-Based Cardiometabolic Risk Classification in Adolescents.Sports (Basel, Switzerland) · 2025Article
- Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation.European journal of clinical investigation · 2025Review
- Mediating role of organized sports participation on the relationship between body fatness and arterial wall thickness among adolescents: ABCD Growth Study.BMC pediatrics · 2025Article
- Mediation of obesity-related variables in the association between physical fitness and cardiometabolic risk in children and adolescents: a systematic review and meta-analysis.BMJ open sport & exercise medicine · 2025Article
- The relationship between healthy lifestyles and cognitive function in Chinese older adults: the mediating effect of depressive symptoms.BMC geriatrics · 2024Article
- Fitness and fatness in children and adolescents: investigating their role in the association between physical activity and cardiometabolic health.Biology of sport · 2024Article
- Cardiorespiratory fitness attenuates the association between fatness and cardiometabolic risk in Chinese children.Frontiers in endocrinology · 2024Article
- Comparison of Several Anthropometric Indices Related to Body Fat in Predicting Cardiorespiratory Fitness in School-Aged Children-A Single-Center Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Association between cardiorespiratory fitness level and insulin resistance in adolescents with various obesity categories.World journal of diabetes · 2023Article
- A Deep Learning Neural Network to Classify Obesity Risk in Portuguese Adolescents Based on Physical Fitness Levels and Body Mass Index Percentiles: Insights for National Health Policies.Behavioral sciences (Basel, Switzerland) · 2023Article
- The Influence of Abdominal Adiposity and Physical Fitness on Obesity Status of Portuguese Adolescents.International journal of environmental research and public health · 2022Article
- Benefits of Physical Activity on Cardiometabolic Diseases in Obese Children and Adolescents.Journal of translational internal medicine · 2022Article
- Cardiometabolic Risk in Children and Adolescents: The Paradox between Body Mass Index and Cardiorespiratory Fitness.Arquivos brasileiros de cardiologia · 2022Article
Corrections and comments
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Authors and funding
11 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study was aimed to analyze the mediation role of cardiorespiratory fitness (CRF) on the association between fatness and cardiometabolic risk scores (CMRs) in European adolescents.
methodsA cross-sectional study was conducted in adolescents (n = 525; 46% boys; 14.1 ± 1.1 years old, mean ± SD) from 10 European cities involved in the Healthy Lifestyle in Europe by Nutrition in Adolescence study. CRF was measured by means of the shuttle run test, while fatness measures included body mass index (BMI), waist to height ratio, and fat mass index estimated from skinfold thicknesses. A clustered CMRs was computed by summing the standardized values of homeostasis model assessment, systolic blood pressure, triglycerides, total cholesterol/high-density lipoprotein cholesterol ratio, and leptin.
resultsLinear regression models indicated that CRF acted as an important and partial mediator in the association between fatness and CMRs in 12-17-year-old adolescents (for BMI: coefficients of the indirect role β = 0.058 (95% confidence interval (95%CI): 0.023-0.101), Sobel test z = 3.11 (10.0% mediation); for waist to height ratio: β = 4.279 (95%CI: 2.242-7.059), z =3.86 (11.5% mediation); and for fat mass index: β = 0.060 (95%CI: 0.020-0.106), z = 2.85 (9.4% mediation); all p < 0.01).
conclusionIn adolescents, the association between fatness and CMRs could be partially decreased with improvements to fitness levels; therefore, CRF contribution both in the clinical field and public health could be important to consider and promote in adolescents independently of their fatness levels.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.