Evidence map›Paper›PMID 33993726›Full record

ReviewHypertension (Dallas, Tex. : 1979)2021

Adrenocorticotropic Hormone-Stimulated Adrenal Venous Sampling Underestimates Surgically Curable Primary Aldosteronism: A Retrospective Cohort Study and Review of Contemporary Studies.

Nicholas Yozamp, Gregory L Hundemer, Marwan Moussa, Jonathan Underhill, Tali Fudim, Barry Sacks, Anand Vaidya

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07298954 (Sequential Combined Versus Single-Strategy Adrenal Venous Sampling for Primary Aldosteronism), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07298954 narecruitingnot on this mapstarted 2025, after this paper: background citation

Sequential Combined Versus Single-Strategy Adrenal Venous Sampling for Primary Aldosteronism: A Multicenter, Randomized Trial

TypeinterventionalSponsorShumin YangRan2025 to 2028Enrolled456ConditionsPrimary AldosteronismArmssequential combined AVS
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Trial
  5. Primary aldosteronism.Nature reviews. Disease primers · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Primary Aldosteronism: State-of-the-Art Review.American journal of hypertension · 2022
    Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nicholas YozampFrom the Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.Y., A.V.).
Gregory L HundemerDivision of Nephrology, Department of Medicine and the Ottawa Hospital Research Institute, University of Ottawa, Canada (G.L.H.).
Marwan MoussaDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.M., J.U., T.F., B.S.).
Jonathan UnderhillDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.M., J.U., T.F., B.S.).
Tali FudimDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.M., J.U., T.F., B.S.).
Barry Sacks
Anand VaidyaFrom the Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.Y., A.V.).
Beth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USUniversity of Ottawa · CA

Funding

TRAINING PROGRAM IN HYPERTENSIONT32HL007609 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ADLER, GAIL KURR · 1985 to 2022
$10.2M
Unrecognized Primary Aldosteronism as a Pathogenic Mechanism for Chronic Kidney Disease in DiabetesR01DK115392 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI Anand Vaidya · 2018 to 2026
$6.0M
Adrenal Origins of Aldosterone ExcessR01DK106618 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI William E Rainey, Aaron Mark Udager · 2016 to 2026
$6.0M
Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in ObesityR01HL153004 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI VAIDYA, ANAND · 2020 to 2024
$4.4M
NHLBI NIH HHS R01 HL153004NHLBI NIH HHS T32 HL007609NIDDK NIH HHS R01 DK106618NIDDK NIH HHS R01 DK115392
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Adrenal GlandsAdrenocorticotropic HormoneAdultAldosteroneFemaleHumansHydrocortisoneHyperaldosteronismMaleMiddle AgedRetrospective StudiesVeinsAdrenocorticotropic HormoneAldosteroneHydrocortisoneadrenocorticotropic hormonecatheterizationconsensusinterventional radiologytreatment outcome

Identifiers

PMID33993726
PMCPMC8192472
OpenAlexW3162750439

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.