Evidence map›Paper›PMID 33993630›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2021

Outcomes of COVID-19 in solid organ transplant recipients: A matched cohort study.

Marcus R Pereira, Selim Arcasoy, Maryjane A Farr, Sumit Mohan, Jean C Emond, Demetra S Tsapepas, Qiuhu Shi, Lawrence Purpura, Anne-Catrin Uhlemann, Jason Zucker and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Clinical outcome in solid organ transplant recipients affected by COVID-19 compared to general population: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Impact of Omicron BA.1 infection on BA.4/5 immunity in transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Incidence and severity of SARS-CoV-2 infections in liver and kidney transplant recipients in the post-vaccination era: Real-life data from Denmark.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  15. Successful liver transplantation in patients with active SARS-CoV-2 infection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  16. Outcomes following SARS-CoV-2 infection in individuals with and without solid organ transplantation-A Danish nationwide cohort study.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  17. Article
  18. Article
  19. Impact of solid organ transplant status on outcomes of hospitalized patients with COVID-19 infection.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marcus R PereiraDepartment of Medicine, Division of Infectious Disease, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0002-9214-9122
Selim ArcasoyLung Transplant Program, Division of Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0003-1906-8577
Maryjane A FarrDepartment of Medicine, Division of Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0003-1066-9368
Sumit MohanDepartment of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0002-5305-9685
Jean C EmondDepartment of Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0003-1642-9242
Demetra S TsapepasDepartment of Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0001-6428-5525
Qiuhu ShiDepartment of Public Health, School of Health Sciences and Practice, New York Medical College, New York, NY, USA.ORCID https://orcid.org/0000-0003-3200-8309
Lawrence PurpuraDepartment of Medicine, Division of Infectious Disease, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0002-2900-6022
Anne-Catrin UhlemannDepartment of Medicine, Division of Infectious Disease, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0002-9798-4768
Jason ZuckerDepartment of Medicine, Division of Infectious Disease, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID https://orcid.org/0000-0001-6987-6412
Elizabeth C VernaDepartment of Medicine, Division of Digestive and Liver Diseases, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Columbia University · USNew York Medical College · US

Funding

Columbia Partnership for Prevention and Control of HIV/AIDS Clinical Trials UnitUM1AI069470 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAGDALENA ELZBIETA SOBIESZCZYK · 2012 to 2026
$44.8M
Columbia Collaborative HIV/AIDS Clinical Trials UnitU01AI069470 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAMMER, SCOTT M · 2007 to 2011
$15.4M
Division of Intramural Research, National Institute of Allergy and Infectious Diseases 5UM1AI069470NIAID NIH HHS U01 AI069470NIAID NIH HHS UM1 AI069470
6 · The paper itself

Abstract

Whether solid organ transplant (SOT) recipients are at increased risk of poor outcomes due to COVID-19 in comparison to the general population remains uncertain. In this study, we compared outcomes of SOT recipients and non-SOT patients hospitalized with COVID-19 in a propensity score matched analysis based on age, race, ethnicity, BMI, diabetes, and hypertension. After propensity matching, 117 SOT recipients and 350 non-SOT patients were evaluated. The median age of SOT recipients was 61 years, with a median time from transplant of 5.68 years. The most common transplanted organs were kidney (48%), followed by lung (21%), heart (19%), and liver (10%). Overall, SOT recipients were more likely to receive COVID-19 specific therapies and to require ICU admission. However, mortality (23.08% in SOT recipients vs. 23.14% in controls, P = .21) and highest level of supplemental oxygen (P = .32) required during hospitalization did not significantly differ between groups. In this propensity matched cohort study, SOT recipients hospitalized with COVID-19 had similar overall outcomes as non-SOT recipients, suggesting that chronic immunosuppression may not be an independent risk factor for poor outcomes in COVID-19.

Indexed as

COVID-19Organ TransplantationCohort StudiesHumansMiddle AgedRetrospective StudiesSARS-CoV-2Transplant RecipientsCOVID-19transplantviral infections

Identifiers

PMID33993630
PMCPMC8209880
OpenAlexW3162598036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.