Evidence map›Paper›PMID 33993492›Full record

ReviewBritish journal of haematology2021

Point-of-care haemoglobin testing in African hospitals: a neglected essential diagnostic test.

Sophie Uyoga, Elizabeth C George, Imelda Bates, Peter Olupot-Olupot, Yami Chimalizeni, Elizabeth M Molyneux, Kathryn Maitland

Open access · hybridAbstract readReview
In one paragraph

Review in British journal of haematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. The silent epidemic: Tackling the burden of anaemia in Africa.African journal of laboratory medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Blood transfusion for children in sub-Saharan Africa: 200 years on.The Lancet. Child & adolescent health · 2023
    Article
  13. Review
  14. Severe malaria.Malaria journal · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Sophie UyogaKenya Medical Research Institute (KEMRI), Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0003-1746-7873
Elizabeth C GeorgeMedical Research Council Clinical Trials Unit (MRC CTU) at University College, London, UK.ORCID 0000-0002-2928-3580
Imelda BatesLiverpool School of Tropical Medicine, Liverpool UK, Liverpool, UK.ORCID 0000-0002-0862-8199
Peter Olupot-OlupotFaculty of Health Sciences, Busitema University, Mbale Regional Referral Hospital, Mbale, Uganda.ORCID 0000-0002-5757-609X
Yami ChimalizeniCollege of Medicine, Malawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.ORCID 0000-0003-0119-804X
Elizabeth M MolyneuxCollege of Medicine, Malawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.ORCID 0000-0001-5479-5900
Kathryn MaitlandKenya Medical Research Institute (KEMRI), Wellcome Trust Research Programme, Kilifi, Kenya.ORCID 0000-0002-0007-0645
Kenya Medical Research Institute · KEUniversity of Liverpool · GBLiverpool School of Tropical Medicine · GBMbale Hospital · UGMRC Clinical Trials Unit at UCL · GB

Funding

Medical Research Council MC_UU_00004/05Medical Research Council MC_UU_12023/26Medical Research Council MR/J012483/1
6 · The paper itself

Abstract

Owing to the rapid turnaround time in the assessment of haemoglobin level by point-of-care tests (POC Hb), these have grown in popularity and scope in large parts of the world. However, whilst POC testing for malaria and HIV remains has been integrated into patient management in Africa, the use of POC haemoglobin testing remains neglected by health services. The main users of transfusions (paediatric, maternity and trauma services) present largely as emergencies. Ward-based POC Hb could result in more rapid and accurate diagnosis of anaemia, contributing to saving of lives and at the same time reduce unnecessary transfusions which deplete the limited supplies of donated blood in Africa. Severe anaemia requiring transfusion is a major cause of paediatric admission in Africa. At a dissemination meeting to discuss the results of a large phase III paediatric transfusion trial and steps to implementation of the findings participants strongly recommended that one of the most pressing actions required was to prioritise the use of POC haemoglobin testing. This would facilitate implementation of the new transfusion algorithm, developed at the meeting, which refines patient management including blood transfusions. We present the rationale for the strongly recommended prioritisation of POC Hb, using paediatric transfusion as an exemplar.

Indexed as

AlgorithmsAnemiaBlood TransfusionPoint-of-Care TestingChildChild, PreschoolClinical Trials, Phase III as TopicFemaleHemoglobinsHumansInfantMalawiMaleRandomized Controlled Trials as TopicUgandaHemoglobinsanaemia in developing worldchildrendiagnostic haematologypaediatric anaemiatransfusion medicine

Identifiers

PMID33993492
PMCPMC7611318
OpenAlexW3160096937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.