Evidence map›Paper›PMID 33993367›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Intraventricular haemorrhage and posthaemorrhagic ventricular dilatation: moving beyond CSF diversion.

Aswin Chari, Conor Mallucci, Andrew Whitelaw, Kristian Aquilina

Open access · hybridAbstract readReview
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Neuroendoscopic lavage for the management of neonatal post-haemorrhagic hydrocephalus: A systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  3. Comparing ventricular access devices and ventriculosubgaleal shunts for posthemorrhagic ventricular dilatation: systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  4. Article
  5. Article
  6. Safety and efficacy of neuroendoscopic lavage for the management of neonatal intraventricular haemorrhage.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. A standardised protocol for neuro-endoscopic lavage for post-haemorrhagic ventricular dilatation: A Delphi consensus approach.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Aswin ChariDepartment of Neurosurgery, Great Ormond Street Hospital, London, UK.ORCID http://orcid.org/0000-0003-0053-147X
Conor MallucciDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, UK.
Andrew WhitelawNeonatal Neuroscience, Translational Health Sciences, University of Bristol, Bristol, UK.
Kristian AquilinaDepartment of Neurosurgery, Great Ormond Street Hospital, London, UK. Kristian.aquilina@gosh.nhs.uk.
Great Ormond Street Hospital · GBUniversity of Bristol · GBUniversity of Liverpool · GB

Funding

Great Ormond Street Hospital Charity (GB) VS0319
6 · The paper itself

Abstract

Advances in medical care have led to more premature babies surviving the neonatal period. In these babies, germinal matrix haemorrhage (GMH), intraventricular haemorrhage (IVH) and posthaemorrhagic ventricular dilatation (PHVD) are the most important determinants of long-term cognitive and developmental outcomes. In this review, we discuss current neurosurgical management of IVH and PHVD, including the importance of early diagnosis of PHVD, thresholds for intervention, options for early management through the use of temporising measures and subsequent definitive CSF diversion. We also discuss treatment options for the evolving paradigm to manage intraventricular blood and its breakdown products. We review the evidence for techniques such as drainage, irrigation, fibrinolytic therapy (DRIFT) and neuroendoscopic lavage in the context of optimising cognitive, neurodevelopmental and quality of life outcomes in these premature infants.

Indexed as

Infant, Premature, DiseasesQuality of LifeCerebral HemorrhageCerebral VentriclesDilatationDilatation, PathologicHumansInfantInfant, NewbornGerminal matrix haemorrhageIntraventricular haemorrhageNeuroendoscopic lavagePosthaemorrhagic ventricular dilatationPrematureTemporising device

Identifiers

PMID33993367
PMCPMC8578081
OpenAlexW3160355493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.