ReviewNeurosurgical review2022
The supplementary motor area syndrome: a neurosurgical review.
Review in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 61 citations in OpenAlex.
- A Pilot Randomized Controlled Trial of Intermittent Theta Burst Stimulation as Stand-Alone Treatment for Post-Stroke Aphasia: Effects on Language and Verbal Functional Magnetic Resonance Imaging (fMRI).Medical science monitor : international medical journal of experimental and clinical research · 2021Trial
- Stage-Dependent Physiotherapy for Recovery From Supplementary Motor Area Syndrome: A Case Report.Brain & NeuroRehabilitation · 2026Article
- Clinical implications of false-negative and false-positive intraoperative transcranial motor evoked potentials in brain tumor surgery.Neurosurgical review · 2026Article
- Altered Regional Brain Activity and Functional Connectivity Between Non-Diabetic and Diabetic Kidney Disease: A Resting-State fMRI Study.Brain and behavior · 2026Article
- Alterations of white matter connectivity in alopecia areata patients.Brain imaging and behavior · 2026Article
- Effect of repetitive transcranial magnetic stimulation modulating supplementary motor area in stroke rehabilitation: Systematic review of randomized controlled trials.AIMS neuroscience · 2026Review
- Comparative efficacy and mechanistic insights of non-invasive neuromodulation and motor rehabilitation on functional reorganization of the supplementary motor area in subacute stroke: a narrative review.Frontiers in physiology · 2026Review
- Functional mapping of the somatotopic organization of the supplementary motor area using navigated repetitive transcranial magnetic stimulation and computer vision-based analysis.Frontiers in neuroscience · 2026Article
- Association of postoperative navigated transcranial magnetic stimulation with accelerated motor recovery after tumor resection in the supplementary motor area.Brain & spine · 2026Article
- Qualitative and quantitative analysis of the callosal projections to prefrontal, frontal motor, and parietal areas in the macaque monkey.Brain structure & function · 2025Article
- Integrated neuroimaging and robotic rehabilitation in chronic stroke: Neural correlates and predictors of motor recovery.Experimental and therapeutic medicine · 2025Article
- Neural mechanisms of lipreading in the Polish-speaking population: effects of linguistic complexity and sex differences.Scientific reports · 2025Article
- Deficits of Attention and Working Memory in Patients with Gliomas of Supplementary Motor Area.Journal of clinical medicine · 2025Article
- Supplementary motor area in speech initiation: A large-scale intracranial EEG evaluation of stereotyped word articulation.iScience · 2025Article
- Presentation, surgical outcome, and supplementary motor area syndrome risk of posterior superior frontal gyrus tumors.Journal of neurosurgery · 2025Article
- Development and testing of a high-risk behavior scale for swimming among Chinese adolescents.Frontiers in psychology · 2025Article
- Asymmetry of the Frontal Aslant Tract and Development of Supplementary Motor Area Syndrome.Cancers · 2024Article
- Frontal lobe disconnection: How I do it.Acta neurochirurgica · 2024Article
- Characteristic Changes of Prefrontal and Motor Areas in Patients with Type 2 Diabetes and Major Depressive Disorder During a Motor Task of Tai Chi Chuan: A Functional Near-Infrared Spectroscopy Study.Brain and behavior · 2024Article
- "Apathetic look" is a valuable indicator of intraoperative supplementary motor area syndrome during awake craniotomy.Neurosurgical review · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The supplementary motor area (SMA) syndrome is a frequently encountered clinical phenomenon associated with surgery of the dorsomedial prefrontal lobe. The region has a known motor sequencing function and the dominant pre-SMA specifically is associated with more complex language functions; the SMA is furthermore incorporated in the negative motor network. The SMA has a rich interconnectivity with other cortical regions and subcortical structures using the frontal aslant tract (FAT) and the frontostriatal tract (FST). The development of the SMA syndrome is positively correlated with the extent of resection of the SMA region, especially its medial side. This may be due to interruption of the nearby callosal association fibres as the contralateral SMA has a particular important function in brain plasticity after SMA surgery. The syndrome is characterized by a profound decrease in interhemispheric connectivity of the motor network hubs. Clinical improvement is related to increasing connectivity between the contralateral SMA region and the ipsilateral motor hubs. Overall, most patients know a full recovery of the SMA syndrome, however a minority of patients might continue to suffer from mild motor and speech dysfunction. Rarely, no recovery of neurological function after SMA region resection is reported.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.