Evidence map›Paper›PMID 33992729›Full record

ReviewAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2021

Transplant Options for Patients With Diabetes and Advanced Kidney Disease: A Review.

Aleksandra Kukla, Pedro Ventura-Aguiar, Matthew Cooper, Eelco J P de Koning, David J Goodman, Paul R Johnson, Duck J Han, Didier A Mandelbrot, Martha Pavlakis, Frantisek Saudek and 3 more

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Continuous Glucose Monitoring Before and After Simultaneous Pancreas-Kidney Transplantation: Insights from a Real-World Clinical Setting.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Article
  4. Review
  5. Simultaneous kidney-islet transplantation from a donor after circulatory death using normothermic regional perfusion.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  6. Article
  7. Generating strategies for a national comeback in pancreas transplantation: A Delphi survey and US conference report.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  8. Article
  9. Cautious Optimism Warranted for Stem Cell-Derived Islet Transplantation in Type 2 Diabetes.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 8 countries.

Aleksandra KuklaDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.
Pedro Ventura-AguiarDivision of Nephrology, Hospital Clinic of Barcelona, Barcelona, Spain.
Matthew CooperMedstar Georgetown Transplant Institute, Washington, DC.
Eelco J P de KoningDepartment of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
David J GoodmanDepartment of Nephrology, St. Vincent's Hospital, Melbourne, Australia.
Paul R JohnsonNuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Duck J HanDivision of Transplantation, Department of Surgery, Asan Medical Center, Seoul, South Korea.
Didier A MandelbrotDivision of Nephrology, Department of Medicine, University of Wisconsin, Madison, WI.
Martha PavlakisDivision of Nephrology, Department of Medicine, Beth Isreal Deaconess Medical Center, Boston, MA.
Frantisek SaudekDiabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Marie-Christine VantyghemCHU Lille, Department of Endocrinology, Diabetology and Metabolism, Inserm U1190, Translational Research for Diabetes, Univ Lille, European Genomic Institute for Diabetes, Lille, France.
Titus AugustineDivision of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology Medicine and Health, Manchester Academic Health Centre, University of Manchester, Manchester, United Kingdom. Electronic address: Titus.Augustine@mft.nhs.uk.
Michael R RickelsDivision of Endocrinology, Diabetes & Metabolism, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. Electronic address: rickels@pennmedicine.upenn.edu.
Asan Medical Center · KRBeth Israel Deaconess Medical Center · USHospital Clínic de Barcelona · ESInserm · FRInstitute of Clinical and Experimental Medicine · CZLeiden University Medical Center · NLMayo Clinic · USMedStar Heart & Vascular Institute · USSt Vincent's Hospital · AUUniversity of Manchester · GBUniversity of Oxford · GBUniversity of Wisconsin–Madison · US

Funding

Glucose Counterregulation in Long Standing Type 1 DiabetesR01DK091331 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI RICKELS, MICHAEL R · 2011 to 2020
$3.8M
NIDDK NIH HHS R01 DK091331
6 · The paper itself

Abstract

Optimal glycemic control in kidney transplant recipients with diabetes is associated with improved morbidity and better patient and allograft survival. Transplant options for patients with diabetes requiring insulin therapy and chronic kidney disease who are suitable candidates for kidney transplantation should include consideration of β-cell replacement therapy: pancreas or islet transplantation. International variation related to national regulatory policies exists in offering one or both options to suitable candidates and is further affected by pancreas/islet allocation policies and transplant waiting list dynamics. The selection of appropriate candidates depends on patient age, coexistent morbidities, the timing of referral to the transplant center (predialysis versus on dialysis) and availability of living kidney donors. Therefore, early referral (estimated glomerular filtration rate < 30 mL/min/1.73 m

Indexed as

Living DonorsDiabetes Mellitus, Type 1Global HealthGraft SurvivalHumansKidney DiseasesKidney TransplantationMorbidityPostoperative ComplicationsTransplantation, Homologouschronic kidney disease (CKD)diabetes mellitushypoglycemia unawarenesskidney transplantationpancreas after kidney transplantation (PAK)reviewsimultaneous islet-kidney transplantation (SIK)simultaneous pancreas-kidney transplantation (SPK)β-cell replacement therapy

Identifiers

PMID33992729
PMCPMC8606031
OpenAlexW3160012466

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.