Evidence map›Paper›PMID 33992687›Full record

ArticleThe Journal of infection2021

Clinical efficacy of nitric oxide nasal spray (NONS) for the treatment of mild COVID-19 infection.

Stephen Winchester, Sarah John, Kashif Jabbar, Isaac John

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in The Journal of infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  18. Click chemistry and drug delivery: A bird's-eye view.Acta pharmaceutica Sinica. B · 2023
    Review
  19. Nasal sprays for treating COVID-19: a scientific note.Pharmacological reports : PR · 2023
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Stephen WinchesterConsultant Medical Virologist, Frimley Health NHS Foundation Trust, Portsmouth Road, Camberley, Surrey GU16 7UJ, United Kingdom. Electronic address: s.winchester@nhs.net.
Sarah JohnMedical Student, University of Cambridge School of Clinical Medicine, Box 111 Cambridge Biomedical Campus, Cambridge CB2 0SP, United Kingdom.
Kashif JabbarClinical Researcher, Ashford and St Peter's Hospitals NHS Foundation Trust, St Peters Hospital, Guildford Road, Chertsey, Surrey, KT16 0PZ, United Kingdom.
Isaac JohnHonorary Senior Lecturer, Royal Holloway University of London, Egham, Surrey, TW20 OEX, United Kingdom; Deputy Director of Research & Development, Ashford and St Peter's Hospitals NHS Foundation Trust, St Peters Hospital, Guildford Road, Chertsey, Surrey, KT16 0PZ, United Kingdom.
Ashford and St Peter's Hospitals NHS Foundation Trust · GBFrimley Health NHS Foundation Trust · GBUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baek et al.

Indexed as

COVID-19Nasal SpraysHumansNitric OxideRNA, ViralSARS-CoV-2Treatment OutcomeNasal SpraysNitric OxideRNA, ViralAntimicrobialAntiviralCoronavirusCOVID-19Nasal SprayNitric oxidePreventionSARS-CoV-2Treatment

Identifiers

PMID33992687
PMCPMC8117664
OpenAlexW3161198291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.