ArticleBMC oral health2021
Clinical characteristics of oral lichen planus and its causal context with dental restorative materials and oral health-related quality of life.
Article in BMC oral health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Curcumin Versus Corticosteroids for Symptomatic Oral Lichen Planus: A Systematic Review and Meta-Analysis.Clinical and experimental dental research · 2025Pooled it
- Inflammation-Driven Epithelial Plasticity in Oral Mucosa Adjacent to Long-Term Restorative Materials: A Retrospective Histopathological and Immunohistochemical Study.Medicina (Kaunas, Lithuania) · 2026Article
- Desquamative Gingivitis Revisited: A Narrative Review on Pathophysiology, Diagnostic Challenges, and Treatment.Medicina (Kaunas, Lithuania) · 2025Review
- Flaxseed Extracts Impact the Cellular Structure of a Keratinocyte Model for Oral Lichen Planus-A Preliminary Study.International journal of molecular sciences · 2025Article
- Review
- Lichen planus with dysphagia: an interdisciplinary, monocentric study of quality of life and depression.Frontiers in medicine · 2025Article
- Oral Lichen Planus: A Narrative Review Navigating Etiologies, Clinical Manifestations, Diagnostics, and Therapeutic Approaches.Journal of clinical medicine · 2024Review
- Oral health related quality of life in head and neck cancer survivors within the first year following treatment: a cross-sectional study in Karachi, Pakistan.Scientific reports · 2024Article
- SDHB reduction promotes oral lichen planus by impairing mitochondrial respiratory function.Annals of translational medicine · 2022Article
- Desquamative Gingivitis in the Context of Autoimmune Bullous Dermatoses and Lichen Planus-Challenges in the Diagnosis and Treatment.Diagnostics (Basel, Switzerland) · 2022Review
- Mercury and Mercury-Containing Preparations: History of Use, Clinical Applications, Pharmacology, Toxicology, and Pharmacokinetics in Traditional Chinese Medicine.Frontiers in pharmacology · 2022Review
- Oral health-related quality of life in erosive/ulcerative oral lichen planus patients.Dental research journal · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to investigate the influence of clinical characteristics and dental restorative materials on oral health-related quality of life in patients with oral lichen planus. In particular, the influences of amalgam and metals were investigated.
methodsA total of 112 patients with clinical and histological features of oral lichen planus from the Department of Cranio-Maxillofacial Surgery at the University Hospital of Münster participated in this prospective study. Clinical parameters of oral lichen planus and the dental restorative materials used were evaluated. Oral health-related quality of life was investigated by using the short form of the German version of the Oral Health Impact Profile (OHIP-14). In addition, physical pain was rated on a visual analogue scale.
resultsThe average OHIP-14 score was 13.54. A high correlation was seen between OHIP and pain. Likewise, higher OHIP-values were seen for male patients, and such as for those patients with non-reticular forms of oral lichen planus (OLP). A local form of OLP is more often seen on female patients, such as with the presence of reticular lichen. In regard to the restorations, the presence of composite restorations is correlated with a local lichen, whereas the presence of gold restorations is often seen with a generalized lichen. Furthermore, the grading of strength of association between mucosal lesion and amalgam/metal was tested. No significant differences revealed the analysis of the relationship between gender, clinical form of OLP, age, and presentation form between the 4 gradings of Thornhill.
conclusionsThe oral health-related quality of life is significantly limited in patients with oral lichen planus. But these OHIP scores are not influenced by the restorative materials. Here, pain severity is the most important aspect. We found no statistical differences in the clinical parameters between patients with amalgam or metal restoration and patients without these restorations. It is not necessary to replace amalgam fillings that are not in direct contact with mucosal surfaces.
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