ArticleBMC plant biology2021
Identification of cell wall-associated kinases as important regulators involved in Gossypium hirsutum resistance to Verticillium dahliae.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 34 citations in OpenAlex.
- A Cotton Laccase Confers Disease Resistance Against Verticillium dahliae by Promoting Cell Wall Lignification.Molecular plant pathology · 2025Article
- Genome-Wide Analysis of the Polygalacturonase Gene Family in Macadamia and Identification of Members Involved in Fruit Abscission.Plants (Basel, Switzerland) · 2025Article
- Characterization and expression of the wall-associated kinase/wall-associated kinase-like (WAK/WAKL) family in response to Botrytis cinerea infection in strawberry (Fragaria×ananassa).BMC plant biology · 2025Article
- Roles of maizeFrontiers in plant science · 2025Article
- Characterization of the wall-associated kinase (WAK) gene family in Gossypium barbadense reveals the positive role of GbWAK5 in salt tolerance.Plant cell reports · 2024Article
- Re-localization of a repeat-containing fungal effector by apoplastic protein Chitinase-like 1 blocks its toxicity.Nature communications · 2024Article
- Insights into ZmWAKL in maize kernel development: genome-wide investigation and GA-mediated transcription.BMC genomics · 2023Article
- Molecular Mechanisms Underlying Potential Pathogen Resistance inPlants (Basel, Switzerland) · 2023Review
- Insights to Gossypium defense response against Verticillium dahliae: the Cotton Cancer.Functional & integrative genomics · 2023Review
- The WAK-like protein RFO1 acts as a sensor of the pectin methylation status in Arabidopsis cell walls to modulate root growth and defense.Molecular plant · 2023Article
- Genome-wide identification and expression analysis of wall-associated kinase (WAK) and WAK-like kinase gene family in response to tomato yellow leaf curl virus infection in Nicotiana benthamiana.BMC plant biology · 2023Article
- Interactions betweenFrontiers in plant science · 2023Review
- A plant cell wall-associated kinase encoding gene is dramatically downregulated during nematode infection of potato.Plant signaling & behavior · 2022Article
- Protein S-Acyl Transferase GhPAT27 Was Associated withPlants (Basel, Switzerland) · 2022Article
- Genome-Wide Identification and Expression Analysis of Wall-Associated Kinase (WAK) Gene Family inPlants (Basel, Switzerland) · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVerticillium wilt, caused by the soil borne fungus Verticillium dahliae, is a major threat to cotton production worldwide. An increasing number of findings indicate that WAK genes participate in plant-pathogen interactions, but their roles in cotton resistance to V. dahliae remain largely unclear.
resultsHere, we carried out a genome-wide analysis of WAK gene family in Gossypium hirsutum that resulted in the identification of 81 putative GhWAKs, which were all predicated to be localized on plasma membrane. In which, GhWAK77 as a representative was further located in tobacco epidermal cells using transient expression of fluorescent fusion proteins. All GhWAKs could be classified into seven groups according to their diverse protein domains, indicating that they might sense different outside signals to trigger intracellular signaling pathways that were response to various environmental stresses. A lot of cis-regulatory elements were predicted in the upstream region of GhWAKs and classified into four main groups including hormones, biotic, abiotic and light. As many as 28 GhWAKs, playing a potential role in the interaction between cotton and V. dahliae, were screened out by RNA-seq and qRT-PCR. To further study the function of GhWAKs in cotton resistance to V. dahliae, VIGS technology was used to silence GhWAKs. At 20 dpi, VIGSed plants exhibited more chlorosis and wilting than the control plants. The disease indices of VIGSed plants were also significantly higher than those of the control. Furthermore, silencing of GhWAKs significantly affected the expression of JA- and SA-related marker genes, increased the spread of V. dahliae in the cotton stems, dramatically compromised V. dahliae-induced accumulation of lignin, H
conclusionOur study presents a comprehensive analysis on cotton WAK gene family for the first time. Expression analysis and VIGS assay provided direct evidences on GhWAKs participation in the cotton resistance to V. dahliae.
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