ArticleNeuroImage2021
Inter-regional BOLD signal variability is an organizational feature of functional brain networks.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Cognitive-Behavioral Predictors of Individual Variability of Functional Connectivity in Healthy Young Adults.Research square · 2026Article
- Regional BOLD variability reflects microstructural maturation and neuronal ensheathment in the preterm infant cortex.Nature communications · 2026Article
- Transdiagnostic Profiles of BOLD Signal Variability in Autism and Schizophrenia Spectrum Disorders: Associations With Cognition and Functioning.Human brain mapping · 2026Article
- Intraindividual Variability in Perceptual-Motor Performance Measured with Virtual Reality Among Military Veterans.Brain sciences · 2026Article
- The biological role of local and global fMRI BOLD signal variability in multiscale human brain organization.Nature communications · 2026Article
- Test-retest reliability of resting-state functional magnetic resonance imaging during deep brain stimulation for Parkinson's disease.NeuroImage. Clinical · 2026Article
- Learning evoked centrality dynamics in the schizophrenia brain: entropy, heterogeneity, and inflexibility of brain networks.Journal of psychiatry & neuroscience : JPN · 2025Article
- Personalized biomarkers of multiscale functional alterations in temporal lobe epilepsy.Nature communications · 2025Article
- The role of brain mechanisms in diabetic peripheral neuropathy: recent advances and comprehensive analysis.Frontiers in cellular neuroscience · 2025Review
- Behavioural stochastic resonance across the lifespan.Cognitive, affective & behavioral neuroscience · 2024Article
- Children's emotional reactivity and negative affect predict future ADHD symptom severity beyond initial ADHD symptom severity.European child & adolescent psychiatry · 2024Article
- Imbalanced temporal states of cortical blood-oxygen-level-dependent signal variability during rest in episodic migraine.The journal of headache and pain · 2024Article
- Reliability of variability and complexity measures for task and task-free BOLD fMRI.Human brain mapping · 2024Article
- Electroencephalography Spectral-power Volatility Predicts Problem-solving Outcomes.Journal of cognitive neuroscience · 2024Article
- Assessment and Training of Perceptual-Motor Function: Performance of College Wrestlers Associated with History of Concussion.Brain sciences · 2024Article
- Leveraging multi-echo EPI to enhance BOLD sensitivity in task-based olfactory fMRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Brain signal variability and executive functions across the life span.Network neuroscience (Cambridge, Mass.) · 2024Article
- The biological role of local and global fMRI BOLD signal variability in human brain organization.bioRxiv : the preprint server for biology · 2023Article
- Similarity in functional connectome architecture predicts teenage grit.Social cognitive and affective neuroscience · 2023Article
- Relation of resting brain signal variability to cognitive and socioemotional measures in an adult lifespan sample.Social cognitive and affective neuroscience · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Neuronal variability patterns promote the formation and organization of neural circuits. Macroscale similarities in regional variability patterns may therefore be linked to the strength and topography of inter-regional functional connections. To assess this relationship, we used multi-echo resting-state fMRI and investigated macroscale connectivity-variability associations in 154 adult humans (86 women; mean age = 22yrs). We computed inter-regional measures of moment-to-moment BOLD signal variability and related them to inter-regional functional connectivity. Region pairs that showed stronger functional connectivity also showed similar BOLD signal variability patterns, independent of inter-regional distance and structural similarity. Connectivity-variability associations were predominant within all networks and followed a hierarchical spatial organization that separated sensory, motor and attention systems from limbic, default and frontoparietal control association networks. Results were replicated in a second held-out fMRI run. These findings suggest that macroscale BOLD signal variability is an organizational feature of large-scale functional networks, and shared inter-regional BOLD signal variability may underlie macroscale brain network dynamics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.