Evidence map›Paper›PMID 33991422›Full record

Observational studyBritish journal of haematology2021

Incidence, characteristics and clinical profile of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in patients with pre-existing primary immune thrombocytopenia (ITP) in Spain.

María E Mingot-Castellano, Patricia Alcalde-Mellado, Cristina Pascual-Izquierdo, Gloria Perez Rus, Aida Calo Pérez, María P Martinez, Francisco J López-Jaime, Lorena Abalo Perez, José R Gonzalez-Porras, Fernanda López Fernández and 6 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in British journal of haematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 1 country.

María E Mingot-CastellanoHospital Universitario Virgen del Rocío, Sevilla, Spain.
Patricia Alcalde-MelladoHospital Universitario Virgen del Rocío, Sevilla, Spain.
Cristina Pascual-IzquierdoHospital Gregorio Marañón, Madrid, Spain.
Gloria Perez RusHospital Gregorio Marañón, Madrid, Spain.
Aida Calo PérezHospital Clínico San Carlos, Mádrid, Spain.
María P MartinezComplejo Asistencial de Ávila, Ávila, Spain.
Francisco J López-JaimeHospital Regional Universitario de Málaga, Málaga, Spain.
Lorena Abalo PerezHospital Severo Ochoa, Madrid, Spain.
José R Gonzalez-PorrasHospital Universitario de Salamanca, Salamanca, Spain.
Fernanda López FernándezHospital Universitario A Coruña, A Coruña, Spain.
Isabel S Caparrós MirandaHospital Clínico Virgen de la Victoria, Málaga, Spain.
Tomás J González-LópezHospital Universitario de Burgos, Burgos, Spain.
María E Moreno BeltránHospital Costa del Sol, Málaga, Spain.
Rebeca Rubio EscuinHospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
Reyes Jimenez BárcenasHospital Universitario Virgen del Rocío, Sevilla, Spain.
on behalf GEPTI (Grupo Español de Trombocitopenia Inmune)
Hospital Universitario Virgen del Rocío · ESHospital General Universitario Gregorio Marañón · ESCatholic University of Ávila · ESComplejo Hospitalario de Salamanca · ESComplexo Hospitalario Universitario A Coruña · ESHospital Clínico San Carlos · ESHospital Clínico Universitario Lozano Blesa · ESHospital Clínico Universitario Virgen de la Victoria · ESHospital Costa del Sol · ESHospital Regional Universitario de Málaga · ESHospital Universitario de Burgos · ESHospital Universitario Severo Ochoa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections are one of the well-known precipitating factors for relapses in patients with immune thrombocytopenia (ITP). Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can sometimes lead to or be associated with thrombocytopenia due to an increase in peripheral platelet destruction from inflammatory hyperactivation. Currently, we do not know if SARS-CoV-2 infection modifies the natural evolution of chronic or persistent ITP or if previous immunosuppression of patients with ITP influences the incidence and severity of coronavirus disease 2019 (COVID-19) in this group. The present study was an observational, multicentre, national series of 32 adult patients with pre-existing ITP and subsequent SARS-CoV-2 infection, collected by the Spanish ITP Group [Grupo Español de Trombocitopenia Inmune (GEPTI)].

Indexed as

AdultAgedAged, 80 and overCOVID-19FemaleHumansIncidenceMaleMiddle AgedPurpura, Thrombocytopenic, IdiopathicSARS-CoV-2SpainchronicCOVID-19ITPpersistentsteroidstreatment

Identifiers

PMID33991422
PMCPMC8239889
OpenAlexW3163779147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.