Trial reportAging clinical and experimental research2021
Cognitive behavioral therapy cannot relieve postoperative pain and improve joint function after total knee arthroplasty in patients aged 70 years and older.
Trial report in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Clinical practice guideline for physical therapist management of total knee arthroplasty: revision 2026.Physical therapy · 2026Guideline
- What proportion of people have long-term pain after total hip or knee replacement? An update of a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Effect of cognitive behavioral therapy on pain, knee function, and psychological status in patients after primary total knee arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- Brief Mindfulness-Based Cognitive Behavioral Therapy is Associated with Faster Recovery in Patients Undergoing Total Knee Arthroplasty: A Pilot Clinical Trial.Pain medicine (Malden, Mass.) · 2023Trial
- Prevention and Treatment of Postsurgical Pain: Pharmacologic and Nonpharmacologic Interventions Across the Surgical Continuum.Clinics in geriatric medicine · 2026Review
- Personalized Multimodal and Opioid-Sparing Analgesia for Postoperative Pain Management: Enhancing Recovery and Addressing the Post-Discharge Gap.Journal of pain research · 2026Review
- Potential Role of Peri-operative Cognitive Behavioral Therapy on Pain and Joint Function After Total Knee Arthroplasty: A Meta-analysis.Indian journal of orthopaedics · 2026Review
- Non-Pharmacological Pain Management for Osteoarthritis: Review Update.Current rheumatology reports · 2025Review
- Upskilling pain relief after surgery: a scoping review of perioperative behavioral intervention efficacy and practical considerations for implementation.Regional anesthesia and pain medicine · 2025Article
- Complementary Approaches to Postoperative Pain Management: A Review of Non-pharmacological Interventions.Pain and therapy · 2025Review
- Article
- Effect of an educational video about ERAS on reducing preoperative anxiety and promoting recovery.Heliyon · 2023Article
- Current evidence does not support the routine use of cognitive behavioural therapy in total knee arthroplasty: A systematic review.Journal of clinical orthopaedics and trauma · 2023Review
- Telemedicine-Based Digital Cognitive Behavioral Intervention for Perioperative Anxiety and Depression for Total Knee Arthroplasty.Journal of pain & relief · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeA randomized controlled trial was conducted to investigate whether cognitive behavioral therapy (CBT) can improve postoperative pain, knee function, and negative emotion in patients aged 70 years and older who underwent total knee arthroplasty (TKA).
methodsThis study used randomized, parallel group, controlled trial to divide the included 90 patients into CBT group and usual care group. The primary outcome measure of the study was the Visual Analogue Scale (VAS) at activity. The secondary outcome measures included the Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Knee Range of Motion (ROM), Oxford Knee Score (OKS), Hospital for Special Surgery Knee Rating Scale (HSS), analgesics dose, and postoperative complications.
results83 patients who met the criteria were randomized into CBT group and usual care group. In the SAS, score of the CBT group decreased by 4.3 points at 7th day and 8.2 at 14th day after surgery with respect to preoperative SAS score, the usual care group increased by 1.5 at 7th day and decreased 1.1 at 14th day, and tended to be similar at 3rd month after surgery. There were no significant differences at 7th and 14th day in SDS, however, score of the CBT group was 5.8 and the usual care group was 1.9 at 3rd month after surgery. No statistically significant differences in VAS at activity, ROM, OKS, HSS, analgesics frequency, and postoperative complications between two groups.
conclusionsCBT was superior to usual care group in relieving anxiety at 7th day and 14th day, and depression at 3rd month, however, CBT cannot relieve postoperative pain and improve joint function after TKA in patients aged 70 years and older.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.