Observational studyNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022
Is new daily persistent headache a fallout of somatization? An observational study.
Observational study in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Exploring the Dynamic Relationship Between Migraine and Functional Neurological Disorders: A Narrative Review.Current pain and headache reports · 2026Review
- Brain networks activated when aggravating baseline chronic pain of an individual with new daily persistent headache: a case study.BMC neurology · 2025Article
- Hallmarks of primary headache: part 4 - rare headache syndromes.The journal of headache and pain · 2025Review
- Repetitive transcranial magnetic stimulation in new daily persistent headache patients: a single arm open label study.The journal of headache and pain · 2024Article
- New Daily Persistent Headache in the Pediatric and Adolescent Population: An Updated Review.Life (Basel, Switzerland) · 2024Review
- Early maladaptive schemas in female patients with migraine and tension-type headache.Scientific reports · 2024Article
- New Daily Persistent Headache (NDPH): Unraveling the Complexities of Diagnosis, Pathophysiology, and Treatment.Current pain and headache reports · 2023Review
- Phenotype of new daily persistent headache: subtypes and comparison to transformed chronic daily headache.The journal of headache and pain · 2023Article
- Clinical characteristics of patients with interstitial cystitis/bladder pain syndrome combined with migraine.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciencesArticle
- Impact of comorbid psychogenic non-epileptic seizures on migraine: An observational study.Journal of neurosciences in rural practiceArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNew daily persistent headache (NDPH) is characterized by daily, persistent headache with clearly remembered onset, preceding events or triggers and treatment refractoriness of headache. The pathophysiology of NDPH is still unresolved. NDPH has been associated with somatoform disorder (DSM 4 TR). Somatization is characterized by vivid memory, disproportionate and persistent thought about symptoms that may explain many characteristics of NDPH. However, tendency towards somatization has not been studied in NDPH patients.
methodsIn this cross-sectional study, we evaluated somatization in NDPH, chronic migraine (CM), and chronic tension type headache (CTTH) by comparing the prevalence of somatic symptom disorder (SSD, DSM-5). We evaluated the past tendencies to somatization by comparing various characteristics of past somatic symptoms (number, duration, type, clearly remembered onset, etc.) between NDPH, CM, and CTTH.
resultsForty-seven patients each of NDPH and CTTH and 46 patients of CM were evaluated. Criteria for SSD was fulfilled by 85.1% of NDPH and CTTH patients and only 45.7% of CM. Past history of somatic symptoms was seen in 70% patients with NDPH, 15.2% CM, and 23.4% CTTH (p<0.001). Median number of past somatic symptoms was higher in NDPH. All NDPH patients clearly remembered the onset of at least one past somatic symptom. None of CM and CTTH patients remembered the onset of past somatic symptoms.
conclusionNDPH patients displayed significant past history of somatization. Continuation of past tendencies to manifest as NDPH suggests that NDPH may be an epiphenomenon of somatization.
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