Evidence map›Paper›PMID 33991216›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2021

Serotonin and beyond-a tribute to Manfred Göthert (1939-2019).

H Bönisch, K B Fink, B Malinowska, G J Molderings, E Schlicker

Open access · hybridAbstract readBiographyHistorical ArticleReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Bibliometric development of Naunyn-Schmiedeberg's Archives of Pharmacology.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

H BönischInstitute of Pharmacology and Toxicology, University of Bonn, Venusberg-Campus 1, 53105, Bonn, Germany.
K B FinkMerz Pharmaceuticals, Frankfurt/Main, Germany.
B MalinowskaDepartment of Physiology and Pathophysiology, Medical University of Białystok, Białystok, Poland.
G J MolderingsInstitute of Human Genetics, University of Bonn, Bonn, Germany.
E SchlickerInstitute of Pharmacology and Toxicology, University of Bonn, Venusberg-Campus 1, 53105, Bonn, Germany. e.schlicker@uni-bonn.de.ORCID http://orcid.org/0000-0001-7708-6998
University of Bonn · DEMedical University of Białystok · PLMerLion Pharma (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Manfred Göthert, who had served Naunyn-Schmiedeberg's Arch Pharmacol as Managing Editor from 1998 to 2005, deceased in June 2019. His scientific oeuvre encompasses more than 20 types of presynaptic receptors, mostly on serotoninergic and noradrenergic neurones. He was the first to identify presynaptic receptors for somatostatin and ACTH and described many presynaptic receptors, known from animal preparations, also in human tissue. In particular, he elucidated the pharmacology of presynaptic 5-HT receptors. A second field of interest included ligand-gated and voltage-dependent channels. The negative allosteric effect of anesthetics at peripheral nACh receptors is relevant for the peripheral clinical effects of these drugs and modified the Meyer-Overton hypothesis. The negative allosteric effect of ethanol at NMDA receptors in human brain tissue occurred at concentrations found in the range of clinical ethanol intoxication. Moreover, the inhibitory effect of gabapentinoids on P/Q Ca

Indexed as

Allosteric RegulationAnimalsHistory, 20th CenturyHistory, 21st CenturyHumansLigand-Gated Ion ChannelsReceptors, NicotinicReceptors, N-Methyl-D-AspartateReceptors, SerotoninSerotoninLigand-Gated Ion ChannelsReceptors, NicotinicReceptors, N-Methyl-D-AspartateReceptors, SerotoninSerotonin5-HT3 receptor structure and function5-HT receptor mutantsAMPA receptorsMode of action of anestheticsMode of action of ethanolMode of action of gabapentinoidsnACh receptorsNMDA receptorsPresynaptic receptorsVoltage-dependent cation channels

Identifiers

PMID33991216
PMCPMC8376721
OpenAlexW3160022009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.