Evidence map›Paper›PMID 33990984›Full record

ArticleBritish journal of clinical pharmacology2021

Real-life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID-19 pneumonia.

Silvia Corcione, Amedeo De Nicolò, Giorgia Montrucchio, Silvia Scabini, Valeria Avataneo, Chiara Bonetto, Simone Mornese Pinna, Jessica Cusato, Francesca Canta, Rosario Urbino and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in British journal of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Therapeutic dilemmas in addressing SARS-CoV-2 infection: Favipiravir versus Remdesivir.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Silvia CorcioneDepartment of Medical Sciences, Infectious Diseases, University of Turin, Italy.ORCID 0000-0003-2949-4297
Amedeo De NicolòLaboratory of Clinical Pharmacology and Pharmacogenetics, Amedeo di Savoia Hospital, Department of Medical Sciences, University of Turin, Italy.
Giorgia MontrucchioDepartment of Surgical Sciences, University of Turin, Italy.
Silvia ScabiniDepartment of Medical Sciences, Infectious Diseases, University of Turin, Italy.
Valeria AvataneoLaboratory of Clinical Pharmacology and Pharmacogenetics, Amedeo di Savoia Hospital, Department of Medical Sciences, University of Turin, Italy.
Chiara BonettoDepartment of Surgical Sciences, University of Turin, Italy.
Simone Mornese PinnaDepartment of Medical Sciences, Infectious Diseases, University of Turin, Italy.
Jessica CusatoLaboratory of Clinical Pharmacology and Pharmacogenetics, Amedeo di Savoia Hospital, Department of Medical Sciences, University of Turin, Italy.
Francesca CantaDepartment of Medical Sciences, Infectious Diseases, University of Turin, Italy.
Rosario UrbinoDepartment of Surgical Sciences, University of Turin, Italy.
Giovanni Di PerriDepartment of Medical Sciences, Infectious Diseases, University of Turin, Italy.
Luca BrazziDepartment of Surgical Sciences, University of Turin, Italy.
Francesco Giuseppe De RosaDepartment of Medical Sciences, Infectious Diseases, University of Turin, Italy.
Antonio D'AvolioLaboratory of Clinical Pharmacology and Pharmacogenetics, Amedeo di Savoia Hospital, Department of Medical Sciences, University of Turin, Italy.ORCID 0000-0002-1321-4126
Department of Medical Sciences · BYOspedale Amedeo di Savoia · ITTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Remdesivir is one of the most encouraging treatments against SARS-CoV-2 infection. After intravenous infusion, RDV is rapidly metabolized (t

Indexed as

COVID-19 Drug TreatmentAdenosine MonophosphateAlanineAntiviral AgentsHumansIntensive Care UnitsSARS-CoV-2Tandem Mass SpectrometryAdenosine MonophosphateAlanineAntiviral AgentsremdesivirCOVID-19ICUpharmacokineticspneumoniaremdesivirSARS-CoV-2

Identifiers

PMID33990984
PMCPMC8239594
OpenAlexW3160812158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.