Evidence map›Paper›PMID 33990913›Full record

ArticleJournal of microbiology (Seoul, Korea)2021

Comparative genomics analysis of Pediococcus acidilactici species.

Zhenzhen Li, Qi Song, Mingming Wang, Junli Ren, Songling Liu, Shancen Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of microbiology (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Frontiers in microbiology · 2026
    Article
  6. Article
  7. Article
  8. Heat-InactivatedInternational journal of molecular sciences · 2025
    Article
  9. Article
  10. DietaryFrontiers in microbiology · 2025
    Article
  11. Draft genome sequence ofMicrobiology resource announcements · 2024
    Article
  12. The Potential ofFoods (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Foods (Basel, Switzerland) · 2023
    Article
  15. Changes in Lacto-FermentedFoods (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhenzhen LiBGI College, Zhengzhou University, Zhengzhou, 450052, China.
Qi SongBGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen, 518120, China.
Mingming WangBGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen, 518120, China.
Junli RenBGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen, 518120, China.
Songling LiuBGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen, 518120, China.
Shancen ZhaoBGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen, 518120, China. zhaoshancen@genomics.cn.
BGI Group (China) · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediococcus acidilactici is a reliable bacteriocin producer and a promising probiotic species with wide application in the food and health industry. However, the underlying genetic features of this species have not been analyzed. In this study, we performed a comprehensive comparative genomic analysis of 41 P. acidilactici strains from various ecological niches. The bacteriocin production of 41 strains were predicted and three kinds of bacteriocin encoding genes were identified in 11 P. acidilactici strains, namely pediocin PA-1, enterolysin A, and colicin-B. Moreover, whole-genome analysis showed a high genetic diversity within the population, mainly related to a large proportion of variable genomes, mobile elements, and hypothetical genes obtained through horizontal gene transfer. In addition, comparative genomics also facilitated the genetic explanation of the adaptation for host environment, which specify the protection mechanism against the invasion of foreign DNA (i.e. CRISPR/Cas locus), as well as carbohydrate fermentation. The 41 strains of P. acidilactici can metabolize a variety of carbon sources, which enhances the adaptability of this species and survival in different environments. This study evaluated the antibacterial ability, genome evolution, and ecological flexibility of P. acidilactici from the perspective of genetics and provides strong supporting evidence for its industrial development and application.

Indexed as

Genome, BacterialAnti-Bacterial AgentsBacteriocinsGenomicsPediococcus acidilacticiAnti-Bacterial AgentsBacteriocinsbacteriocincomparative genomicsgenetic diversitypan-genomePediococcus acidilactici

Identifiers

PMID33990913
OpenAlexW3161788469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.