Evidence map›Paper›PMID 33990899›Full record

ArticleLasers in medical science2022

MMP-3 plays a major role in calcium pantothenate-promoted wound healing after fractional ablative laser treatment.

Sebastian Huth, Laura Huth, Yvonne Marquardt, Maria Cheremkhina, Ruth Heise, Jens Malte Baron

Open access · hybridAbstract read
In one paragraph

Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. An Overview of the Mechanisms of Fractional COLasers in medical science · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Evaluation of Full Thickness Wounds Following Application of a Visco-Liquid Hemostat in a Swine Model.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. IL-33 and IL-37: A Possible Axis in Skin and Allergic Diseases.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sebastian Huth *Department of Dermatology and Allergology, Medical Faculty RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany. shuth@ukaachen.de.ORCID http://orcid.org/0000-0003-4701-3864
Laura Huth *Department of Dermatology and Allergology, Medical Faculty RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.
Yvonne MarquardtDepartment of Dermatology and Allergology, Medical Faculty RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.
Maria CheremkhinaDepartment of Dermatology and Allergology, Medical Faculty RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.
Ruth HeiseDepartment of Dermatology and Allergology, Medical Faculty RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.
Jens Malte BaronDepartment of Dermatology and Allergology, Medical Faculty RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.
RWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ablative fractional laser treatment leads to a loss of matrix metalloproteinase-3 (MMP-3) expression; therefore, in the present in vitro study, we addressed the role of MMP-3 and its regulation by calcium pantothenate in wound healing processes at the molecular level. Utilizing confocal laser microscopy, we investigated MMP-3 protein expression in fractional ablative CO

Indexed as

Lasers, GasPantothenic AcidMatrix Metalloproteinase 3SkinWound HealingMatrix Metalloproteinase 3Pantothenic Acid3D skin modelCalcium pantothenateDexpanthenolMMP-3Wound healing

Identifiers

PMID33990899
PMCPMC8918166
OpenAlexW3160769073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.