Evidence map›Paper›PMID 33990847›Full record

ArticleArchives of women's mental health2021

Trauma exposure and stress-related disorders in a large, urban, predominantly African-American, female sample.

Rachel L Gluck, Georgina E Hartzell, Hayley D Dixon, Vasiliki Michopoulos, Abigail Powers, Jennifer S Stevens, Negar Fani, Sierra Carter, Ann C Schwartz, Tanja Jovanovic and 3 more

Open access · greenAbstract read
In one paragraph

Article in Archives of women's mental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 83 citations in OpenAlex.

  1. Trial
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  3. Hormonal mechanisms of women's risk in the face of traumatic stress.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  9. Racial Discrimination-Related Interoceptive Network Disruptions: A Pathway to Disconnection.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Rachel L GluckDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Georgina E HartzellDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Hayley D DixonDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Vasiliki MichopoulosDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA. vmichop@emory.edu.
Abigail PowersDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Jennifer S StevensDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Negar FaniDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Sierra CarterDepartment of Psychology, Georgia State University, Atlanta, GA, USA.
Ann C SchwartzDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Tanja JovanovicDepartment of Psychiatry and Behavioral Neuroscience, Wayne State University, Detroit, MI, USA.
Kerry J ResslerDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Bekh BradleyDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Charles F GillespieDepartment of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.
Emory University · USAtlanta Medical Center · USCenter for Anxiety and Depression · USGeorgia State University · USWayne State University · US

Funding

X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 1985 to 2007
$21.3M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Vasiliki Michopoulos · 2018 to 2026
$12.2M
Institute for Clinical and Translational ResearchUL1TR000424 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$6.0M
Emory University BIRCWH ProgramK12HD085850 · NICHD · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, STERK, CLAIRE E · 2015 to 2023
$4.4M
The effects of pregnancy on post traumatic symptoms and fear physiology in traumatized African American womenR01MH115174 · NIMH · EMORY UNIVERSITY · PI MICHOPOULOS, VASILIKI · 2018 to 2022
$3.7M
Mechanisms of Intergenerational Impact of Maternal TraumaR01HD071982 · NICHD · EMORY UNIVERSITY · PI BRADLEY, BEKH · 2013 to 2017
$2.1M
Development, Trauma, and Genotype Effects on Biomarkers of Anxiety in ChildrenR01MH100122 · NIMH · EMORY UNIVERSITY · PI JOVANOVIC, TANJA · 2013 to 2017
$1.9M
Stress-Related Psychobiology and Inflammation in Diabetic African-American WomenR01MH099211 · NIMH · EMORY UNIVERSITY · PI GILLESPIE, CHARLES FREDERICK · 2013 to 2017
$1.9M
Synaptic Plasticity and Extinction of FearK01MH069884 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J · 2004 to 2007
$654k
National Institute of Child Health and Human Development HD071982NCATS NIH HHS UL1 TR000424NCRR NIH HHS M01 RR000039NIA NIH HHS AG062334NIA NIH HHS U54 AG062334NICHD NIH HHS K12 HD085850NICHD NIH HHS R01 HD071982NIMH NIH HHS K01 MH069884NIMH NIH HHS MH069884NIMH NIH HHS MH099211NIMH NIH HHS MH100122NIMH NIH HHS MH115174NIMH NIH HHS R01 MH099211NIMH NIH HHS R01 MH100122NIMH NIH HHS R01 MH115174
6 · The paper itself

Abstract

The current study investigated the relationship between trauma exposure and psychopathology in a sample of predominately African-American women of low socioeconomic status (SES). Women (N = 7430) were recruited from medical clinics at two large public hospitals in Atlanta, GA, from 2005 to 2017. Women were assessed for sociodemographics, life-course trauma burden, posttraumatic stress disorder (PTSD), and major depressive disorder (MDD) utilizing self-report and structured clinical interview assessments. The effects of trauma exposure on current and lifetime PTSD and MDD were examined. Ninety-one percent of women reported trauma exposure, 83% reported a monthly household income of less than $2000, and 41% reported a history of arrest. Regarding psychiatric diagnoses, 30.8% met the criteria for probable MDD, and 32.3% met the criteria for probable PTSD. History of childhood abuse and total lifetime trauma significantly increased PTSD and depressive symptoms with additional incremental trauma exposure. PTSD and depressive symptom scores (95% CI) increased from 5.5 (5.0-6.1) and 8.4 (7.9-9.0) in the no trauma group to 20.8 (20.1-21.5) and 20.4 (19.7-21.2), respectively, in those exposed to four or more types of trauma. These results show high rates of adult and childhood trauma exposure, PTSD, MDD, and an additive effect of lifetime trauma exposure on the development of PTSD and MDD in a sample of low SES African-American women. These findings bring light to the high psychiatric symptom burden in this population and call for increased availability of interventions to address symptoms as well as policies aimed at reducing trauma exposure across the lifespan.

Indexed as

Adult Survivors of Child AbuseChild AbuseMajor Depressive DisorderStress Disorders, Post-TraumaticAdultBlack or African AmericanChildFemaleHumansChild abuseDepressionPTSDTraumaWomen

Identifiers

PMID33990847
PMCPMC9261917
OpenAlexW3162256943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.