GuidelineJournal of perinatology : official journal of the California Perinatal Association2021
Treatment of positive urine cultures in the neonatal intensive care unit: a guideline to reduce antibiotic utilization.
Guideline in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Urinary tract infection in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- A Systematic Review of the Accuracy and Reliability of Pyuria in Diagnosing Pediatric Urinary Tract Infections.Cureus · 2025Review
- Urinary tract infections in very premature neonates: the definition dilemma.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pediatric definition of bacterial urinary tract infection (UTI) is >50,000 colony forming units (CFU) of a single organism on catheterized culture or 10,000-50,000 CFU with pyuria on urinalysis. LOCAL PROBLEM: The diagnosis of UTI in our NICU is clinician-dependent and not based on the accepted pediatric definition.
methodsA retrospective review of positive urine cultures between 2015 and 2017 was performed.
interventionA treatment guideline for positive urine cultures was adopted and PDSA methodology utilized for incremental improvements.
resultsFor 909 pre-intervention neonates, 26 of 38 positive urine cultures were treated for UTI but only 23% (6/26) met the pediatric definition. For 644 post-guideline neonates, only 7 of 25 positive urine cultures were treated and 86% met guideline criteria with no increase in urosepsis.
conclusionsA guideline to treat positive urine cultures resulted in a decreased rate of UTI diagnosis and thus prevented unnecessary antibiotic exposure.
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