Evidence map›Paper›PMID 33990643›Full record

Observational studyScientific reports2021

Predictive SNPs for β

Thongperm Munkongdee, Sissades Tongsima, Chumpol Ngamphiw, Pongsakorn Wangkumhang, Chayanon Peerapittayamongkol, Hafizah Binti Hashim, Suthat Fucharoen, Saovaros Svasti

Open access · goldAbstract readObservational StudyValidation Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. The genetics of pain.BJA education · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Thongperm MunkongdeeDepartment of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Sissades TongsimaNational Biobank of Thailand (NBT), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Chumpol NgamphiwNational Biobank of Thailand (NBT), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Pongsakorn WangkumhangNational Biobank of Thailand (NBT), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Chayanon PeerapittayamongkolDepartment of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Hafizah Binti HashimPathology Department, Hospital Sultanah Bahiyah, Kedah, Malaysia.
Suthat FucharoenDepartment of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Saovaros SvastiThalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand. saovaros.sva@mahidol.ac.th.ORCID 0000-0001-8334-9838
National Science and Technology Development Agency · THSiriraj Hospital · THHospital Sultanah Bahiyah · MYMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Thalassemia/HbE disease has a wide spectrum of clinical phenotypes ranging from asymptomatic to dependent on regular blood transfusions. Ability to predict disease severity is helpful for clinical management and treatment decision making. A thalassemia severity score has been developed from Mediterranean β-thalassemia patients. However, different ethnic groups may have different allele frequency and linkage disequilibrium structures. Here, Thai β

Indexed as

Severity of Illness IndexAdolescentAdultAsian Peoplebeta-ThalassemiaChildChild, PreschoolCohort StudiesFemaleGene FrequencyGenome-Wide Association StudyGTP-Binding ProteinsHemoglobin EHumansInfantInfant, NewbornBCL11A protein, humanGTP-Binding ProteinsHBS1L protein, humanHemoglobin EMYB protein, humanProto-Oncogene Proteins c-mybRepressor Proteins

Identifiers

PMID33990643
PMCPMC8121782
OpenAlexW3163184887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.