Evidence map›Paper›PMID 33990613›Full record

ArticleNPJ biofilms and microbiomes2021

Real-time monitoring of ruminal microbiota reveals their roles in dairy goats during subacute ruminal acidosis.

Xiaodong Chen, Xiaodong Su, Jilong Li, Yuntian Yang, Peiyue Wang, Fang Yan, Junhu Yao, Shengru Wu

Open access · goldAbstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 108 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xiaodong ChenCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Xiaodong SuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Jilong LiCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Yuntian YangCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Peiyue WangCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Fang YanCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Junhu YaoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China. yaojunhu2004@sohu.com.
Shengru WuCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China. wushengru2013@163.com.ORCID http://orcid.org/0000-0002-1046-3477
Northwest A&F University · CNKarolinska Institutet · SENorth West Agriculture and Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ruminal microbiota changes frequently with high grain diets and the occurrence of subacute ruminal acidosis (SARA). A grain-induced goat model of SARA, with durations of a significant decrease in the rumen pH value to less than 5.6 and an increase in the rumen lipopolysaccharides concentration, is constructed for real-time monitoring of bacteria alteration. Using 16 S rRNA gene sequencing, significant bacterial differences between goats from the SARA and healthy groups are identified at every hour for six continuous hours after feeding. Moreover, 29 common differential genera between two groups over 6 h after feeding are all related to the altered pH and lipopolysaccharides. Transplanting the microbiota from donor goats with SARA could induce colonic inflammation in antibiotic-pretreated mice. Overall, significant differences in the bacterial community and rumen fermentation pattern between the healthy and SARA dairy goats are real-time monitored, and then tested using ruminal microbe transplantation to antibiotic-treated mice.

Indexed as

AcidosisAnimalsBiodiversityFermentationGastrointestinal MicrobiomeGene Expression ProfilingGoatsRumenSheepSheep DiseasesTranscriptome

Identifiers

PMID33990613
PMCPMC8121909
OpenAlexW3162544209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.