Evidence map›Paper›PMID 33990604›Full record

ArticleNature communications2021

Quality control of protein reagents for the improvement of research data reproducibility.

Ario de Marco, Nick Berrow, Mario Lebendiker, Maria Garcia-Alai, Stefan H Knauer, Blanca Lopez-Mendez, André Matagne, Annabel Parret, Kim Remans, Stephan Uebel and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Metal-Dependent Effects and Crowding Robustness of Pseudomonas fluorescens Esterase I.Chembiochem : a European journal of chemical biology · 2026
    Article
  3. Structural basis ofbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Production of Antibody Fragments Suitable for 1:1, Site-Specific Labeling.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ario de MarcoLab of Environmental and Life Sciences, University of Nova Gorica, Vipava, Vipava, Slovenia.
Nick BerrowProtein Expression Core Facility, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0002-6104-4117
Mario LebendikerProtein Purification Facility, Wolfson Centre for Applied Structural Biology, Edmund J. Safra Campus - The Hebrew University of Jerusalem, Jerusalem, Israel.
Maria Garcia-AlaiEuropean Molecular Biology Laboratory (EMBL), Hamburg Outstation, Hamburg, Germany.
Stefan H KnauerBiochemistry IV - Biopolymers, University of Bayreuth, Bayreuth, Germany.ORCID 0000-0002-4143-0694
Blanca Lopez-MendezProtein Production and Characterization Platform, Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark.ORCID 0000-0001-8541-4904
André MatagneLaboratory of Enzymology and Protein Folding, Centre for Protein Engineering, Department of Life Sciences, University of Liège, Building B6C, Allée du 6 Août, 13, Liège, Belgium.
Annabel ParretEuropean Molecular Biology Laboratory (EMBL), Hamburg Outstation, Hamburg, Germany.ORCID 0000-0003-0635-8890
Kim RemansProtein Expression and Purification Core Facility, EMBL Heidelberg, Heidelberg, Germany.
Stephan UebelCharles River Laboratories, Beerse, Belgium.ORCID 0000-0002-3726-3942
Bertrand RaynalInstitut Pasteur, Plateforme de Biophysique moléculaire, Department of Structural Biology and Chemistry, Paris, France. bertrand.raynal@pasteur.fr.ORCID 0000-0001-5634-0408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHumansIndicators and ReagentsProteinsQuality ControlReproducibility of ResultsIndicators and ReagentsProteins

Identifiers

PMID33990604
PMCPMC8121922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.