Evidence map›Paper›PMID 33990294›Full record

Observational studyBritish journal of sports medicine2021

Lower step rate is associated with a higher risk of bone stress injury: a prospective study of collegiate cross country runners.

Stephanie A Kliethermes, Mikel R Stiffler-Joachim, Christa M Wille, Jennifer L Sanfilippo, Pedro Zavala, Bryan C Heiderscheit

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in British journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. The Effect of Running Speed on Cadence and Running Kinetics.International journal of sports physical therapy · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Bone stress injuries.Nature reviews. Disease primers · 2022
    Review
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stephanie A KliethermesDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA kliethermes@ortho.wisc.edu.ORCID http://orcid.org/0000-0001-9756-7406
Mikel R Stiffler-JoachimDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Christa M WilleDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jennifer L SanfilippoBadger Athletic Performance, University of Wisconsin Madison, Madison, Wisconsin, USA.
Pedro ZavalaBadger Athletic Performance, University of Wisconsin Madison, Madison, Wisconsin, USA.
Bryan C HeiderscheitDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA.
University of Wisconsin–Madison · US

Funding

NRSA Training CoreTL1TR002375 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Vivek Prabhakaran · 2017 to 2026
$8.4M
NCATS NIH HHS TL1 TR002375
6 · The paper itself

Abstract

objectivesTo determine if running biomechanics and bone mineral density (BMD) were independently associated with bone stress injury (BSI) in a cohort of National Collegiate Athletic Association Division I cross country runners.

methodsThis was a prospective, observational study of 54 healthy collegiate cross country runners over three consecutive seasons. Whole body kinematics, ground reaction forces (GRFs) and BMD measures were collected during the preseason over 3 years via motion capture on an instrumented treadmill and total body densitometer scans. All medically diagnosed BSIs up to 12 months following preseason data collection were recorded. Generalised estimating equations were used to identify independent risk factors of BSI.

resultsUnivariably, step rate, centre of mass vertical excursion, peak vertical GRF and vertical GRF impulse were associated with BSI incidence. After adjusting for history of BSI and sex in a multivariable model, a higher step rate was independently associated with a decreased risk of BSI. BSI risk decreased by 5% (relative risk (RR): 0.95; 95% CI 0.91 to 0.98) with each one step/min increase in step rate. BMD z-score was not a statistically significant risk predictor in the final multivariable model (RR: 0.93, 95% CI 0.85 to 1.03). No other biomechanical variables were found to be associated with BSI risk.

conclusionLow step rate is an important risk factor for BSI among collegiate cross country runners and should be considered when developing comprehensive programmes to mitigate BSI risk in distance runners.

Indexed as

Bone DensityAnalysis of VarianceAthletesBiomechanical PhenomenaFemaleFractures, StressHumansIncidenceMaleProspective StudiesRiskRunningSeasonsSex FactorsStudentsTime Factorsbiomechanicsbone mineral densityinjuriesrunning

Identifiers

PMID33990294
PMCPMC8336536
OpenAlexW3160433495

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.