Trial reportThe Journal of international medical research2021
Development and external validation of a nomogram predicting overall survival after curative resection of colon cancer.
Trial report in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- External Validation of the ARCAD Nomogram in a Real-World Cohort with Stage 4 Colorectal Cancer.Cancers · 2026Article
- Constructing a nomogram to predict overall survival of colon cancer based on computed tomography characteristics and clinicopathological factors.World journal of gastrointestinal oncology · 2024Article
- Predicting mortality and recurrence in colorectal cancer: Comparative assessment of predictive models.Heliyon · 2024Article
- Prognostic nomogram in patients with right-sided colon cancer after colectomy: a surveillance, epidemiology, and end results-based study.Frontiers in oncology · 2024Article
- Survival prediction and prognostic factors in colorectal cancer after curative surgery: insights from cox regression and neural networks.Scientific reports · 2023Article
- Construction and validation of a nomogram model for predicting the overall survival of colorectal cancer patients.BMC surgery · 2023Article
- A nomogram for individually predicting the overall survival in colonic adenocarcinoma patients presenting with perineural invasion: a population study based on SEER database.Frontiers in oncology · 2023Article
- Nomogram for Prediction of Postoperative Morbidity in Patients with Colon Cancer Requiring Emergency Therapy.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Machine Learning-Based Prognostic Prediction Models of Non-Metastatic Colon Cancer: Analyses Based on Surveillance, Epidemiology and End Results Database and a Chinese Cohort.Cancer management and research · 2022Article
- Machine learning based prognostic model of Chinese medicine affecting the recurrence and metastasis of I-III stage colorectal cancer: A retrospective study in China.Frontiers in oncology · 2022Article
- Construction of a Prognostic Nomogram for Colorectal Cancer Patients with Fewer than Twelve Lymph Nodes Examined: a Population-Based Study in the SEER Database and China.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo develop and externally validate a prognostic nomogram to predict overall survival (OS) in patients with resectable colon cancer.
methodsData for 50,996 patients diagnosed with non-metastatic colon cancer were retrieved from the Surveillance, Epidemiology, and End Results (SEER) database. Patients were assigned randomly to the training set (n = 34,168) or validation set (n = 16,828). Independent prognostic factors were identified by multivariate Cox proportional hazards regression analysis and used to construct the nomogram. Harrell's C-index and calibration plots were calculated using the SEER validation set. Additional external validation was performed using a Chinese dataset (n = 342).
resultsHarrell's C-index of the nomogram for OS in the SEER validation set was 0.71, which was superior to that using the 7th edition of the American Joint Committee on Cancer TNM staging (0.59). Calibration plots showed consistency between actual observations and predicted 1-, 3-, and 5-year survival. Harrell's C-index (0.72) and calibration plot showed excellent predictive accuracy in the external validation set.
conclusionsWe developed a nomogram to predict OS after curative resection for colon cancer. Validation using the SEER and external datasets revealed good discrimination and calibration. This nomogram may help predict individual survival in patients with colon cancer.
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