Evidence map›Paper›PMID 33990035›Full record

ArticleBiosensors & bioelectronics2021

An intelligent face mask integrated with high density conductive nanowire array for directly exhaled coronavirus aerosols screening.

Qiannan Xue, Xinyuan Kan, Zhihao Pan, Zheyu Li, Wenwei Pan, Feng Zhou, Xuexin Duan

Open access · greenAbstract read
In one paragraph

Article in Biosensors & bioelectronics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qiannan XueState Key Laboratory of Precision Measuring Technology & Instruments, School of Precision Instruments and Optoelec-tronics Engineering, Tianjin University, Tianjin, 300072, China.
Xinyuan KanState Key Laboratory of Precision Measuring Technology & Instruments, School of Precision Instruments and Optoelec-tronics Engineering, Tianjin University, Tianjin, 300072, China.
Zhihao PanState Key Laboratory of Precision Measuring Technology & Instruments, School of Precision Instruments and Optoelec-tronics Engineering, Tianjin University, Tianjin, 300072, China.
Zheyu LiState Key Laboratory of Precision Measuring Technology & Instruments, School of Precision Instruments and Optoelec-tronics Engineering, Tianjin University, Tianjin, 300072, China.
Wenwei PanState Key Laboratory of Precision Measuring Technology & Instruments, School of Precision Instruments and Optoelec-tronics Engineering, Tianjin University, Tianjin, 300072, China.
Feng ZhouState Key Laboratory of Precision Measuring Technology & Instruments, School of Precision Instruments and Optoelec-tronics Engineering, Tianjin University, Tianjin, 300072, China.
Xuexin DuanState Key Laboratory of Precision Measuring Technology & Instruments, School of Precision Instruments and Optoelec-tronics Engineering, Tianjin University, Tianjin, 300072, China. Electronic address: xduan@tju.edu.cn.
Tianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current ongoing outbreak of Coronavirus Disease 2019 (COVID-19) has globally affected the lives of more than one hundred million people. RT-PCR based molecular test is recommended as the gold standard method for diagnosing current infections. However, transportation and processing of the clinical sample for detecting virus require an expert operator and long processing time. Testing device enables on-site virus detection could reduce the sample-to-answer time, which plays a central role in containing the pandemic. In this work, we proposed an intelligent face mask, where a flexible immunosensor based on high density conductive nanowire array, a miniaturized impedance circuit, and wireless communication units were embedded. The sub-100 nm size and the gap between the neighbored nanowires facilitate the locking of nanoscale virus particles by the nanowire arrays and greatly improve the detection efficiency. Such a point-of-care (POC) system was demonstrated for coronavirus 'spike' protein and whole virus aerosol detection in simulated human breath. Detection of viral concentration as low as 7 pfu/mL from the atomized sample of coronavirus aerosol mimic was achieved in only 5 min. The POC systems can be readily applied for preliminary screening of coronavirus infections on-site and may help to understand the COVID-19 progression while a patient is under prescribed therapy.

Indexed as

AerosolCoronavirusImmunosensorIntelligent sensorNanowires

Identifiers

PMID33990035
PMCPMC8091738
OpenAlexW3157935203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.