ReviewBehavioural brain research2021
Central amygdala circuits in valence and salience processing.
Review in Behavioural brain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? - a systematic review.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- Cannabinoid modulation of central amygdala population dynamics during threat investigation.Nature communications · 2026Article
- Amygdalostriatal transition zone neurons encode sustained cue responses to guide defensive behaviors.Neuron · 2026Article
- Chronic stress-induced hypertension: beyond sympathetic activation to autonomic and psychiatric dysregulation.Molecular psychiatry · 2026Article
- Mesocorticolimbic connectivity and motivational sensitivity: sex-specific effects of puberty in early adolescence.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Neural representation of emotional valence in human amygdala and surrounding regions.NeuroImage · 2026Article
- The Role of the Ventral Tegmental Area in Reward and Addiction: A Comprehensive Review.Neurosciences (Riyadh, Saudi Arabia) · 2026Review
- A neural circuit basis for reward-induced suppression of fear generalization and enhancement of fear extinction.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- From hidden springs to endless oceans: exploring the complementary roles of the amygdala and hippocampus in phenomenal experience.Neuroscience of consciousness · 2026Article
- dCA1 cells encode and update contextual place preference.Frontiers in systems neuroscience · 2026Article
- Sex differences in response to violence: role of salience network expansion and connectivity on depression.Translational psychiatry · 2025Article
- Novel potential pharmacological approaches in treating eating disorders comorbid with substance use disorders.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025Review
- Neural circuit plasticity transforms infant neglect into maternal care.Research square · 2025Article
- Integration of Glucagon-Like Peptide 1 Receptor Actions Through the Central Amygdala.Endocrinology · 2025Review
- Article
- Cerebral topographies of perceived and felt emotions.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation.bioRxiv : the preprint server for biology · 2024Article
- Generation and Characterization of a NovelThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Altered Lateral Prefrontal Cortex Functioning During Emotional Interference Resistance Is Associated With Affect Lability in Adults With Persisting Symptoms of Attention-Deficit/Hyperactivity Disorder From Childhood.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Association among childhood adversity and susceptibility to interference during varying salience: two studies in healthy males.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Behavioral responses to environmental stimuli are dictated by the affective valence of the stimulus, good (positive valence) or bad (negative valence). These stimuli can innately elicit an affective response that promotes approach or avoidance behavior. In addition to innately valenced stimuli, valence can also be assigned to initially neutral stimuli through associative learning. A stimulus of a given valence can vary in salience depending on the strength of the stimulus, the underlying state of the animal, and the context of the stimulus presentation. Salience endows the stimulus with the ability to direct attention and elicit preparatory responses to mount an incentive-based motivated behavior. The central nucleus of the amygdala (CeA) has emerged as an early integration point for valence and salience detection to engage preparatory autonomic responses and behavioral posturing in response to both aversive and appetitive stimuli. There are numerous cell types in the CeA that are involved in valence and salience processing through a variety of connections, and we will review the recent progress that has been made in identifying these circuit elements and their roles in these processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.