ArticlePloS one2021
Family-centered music therapy-Empowering premature infants and their primary caregivers through music: Results of a pilot study.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Effectiveness of music therapy intervention on parent-infant attachment and parental anxiety in premature infants care: a systematic review and meta-analysis.Pediatric research · 2026Pooled it
- Pooled it
- Research on music therapy from 2013 to 2022: a bibliometric and visualized study.Frontiers in psychiatry · 2024Pooled it
- Musical and vocal interventions to improve neurodevelopmental outcomes for preterm infants.The Cochrane database of systematic reviews · 2023Pooled it
- Music Therapy in Preterm Infants Reduces Maternal Distress.International journal of environmental research and public health · 2022Trial
- Effect of Continuous Nutrition Management Intervention on Nutritional Status and Development of Premature Infants Based on Mobile Medical APP.Computational and mathematical methods in medicine · 2022Trial
- Maternal Anxiety, Infant Stress, and the Role of Live-Performed Music Therapy during NICU Stay in The Netherlands.International journal of environmental research and public health · 2021Trial
- Impact of live music therapy compared with storytelling on maternal depression and psychological distress in mothers of preterm infants: a secondary analysis of a randomized controlled trial.Maternal health, neonatology and perinatology · 2026Article
- Unveiling the Humanizing and Therapeutic Values of Live Music in Healthcare Settings: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Challenges and limitations of evaluating the efficacy of music intervention for preterm infants: auditory development, methodological heterogeneity, medical complexity, parental involvement and environmental barriers.Frontiers in pediatrics · 2026Article
- Interventions to support postpartum health and well-being of parents with infants in neonatal intensive care units: a scoping review.Frontiers in health services · 2026Review
- Developmental care for preterm infants: a scoping review of interventions, outcomes, and implementation contexts.Frontiers in pediatrics · 2026Review
- Impact of Music Therapy on Neurodevelopment of Preterm Infants and Functional Improvement in Children with Neurological Deficits.Pediatric reports · 2025Review
- Music Therapy with Preterm Infants and Their Families after Hospital Discharge: An Integrative Review.International journal of environmental research and public health · 2024Review
- Music therapy modulates mothers' perception of their preterm infants.Frontiers in psychology · 2023Article
- Article
- Perception of Therapeutic Music in Community Settings.Global advances in integrative medicine and healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Neonatal Intensive Care Units (NICUs) premature infants are exposed to various acoustic, environmental and emotional stressors which have a negative impact on their development and the mental health of their parents. Family-centred music therapy bears the potential to positively influence these stressors. The few existing studies indicate that interactive live-improvised music therapy interventions both reduce parental stress factors and support preterm infants' development.
methodsThe present randomized controlled longitudinal study (RCT) with very low and extremely low birth weight infants (born <30+0 weeks of gestation) and their parents analyzed the influence of music therapy on both the physiological development of premature infants and parental stress factors. In addition, possible interrelations between infant development and parental stress were explored. 65 parent-infant-pairs were enrolled in the study. The treatment group received music therapy twice a week from the 21st day of life till discharge from hospital. The control group received treatment as usual.
resultsCompared to the control group, infants in the treatment group showed a 11.1 days shortening of caffeine therapy, 12.1 days shortening of nasogastric/ orogastric tube feed and 15.5 days shortening of hospitalization, on average. While these differences were not statistically significant, a factor-analytical compound measure of all three therapy durations was. From pre-to-post-intervention, parents showed a significant reduction in stress factors. However, there were no differences between control and treatment group. A regression analysis showed links between parental stress factors and physiological development of the infants.
conclusionThis pilot study suggests that a live-improvised interactive music therapy intervention for extremely and very preterm infants and their parents may have a beneficial effect on the therapy duration needed for premature infants before discharge from hospital is possible. The study identified components of the original physiological variables of the infants as appropriate endpoints and suggested a slight change in study design to capture possible effects of music therapy on infants' development as well. Further studies should assess both short-term and long-term effects on premature infants as well as on maternal and paternal health outcomes, to determine whether a family-centered music therapy, actually experienced as an added value to developmental care, should be part of routine care at the NICU.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.