Evidence map›Paper›PMID 33989106›Full record

Trial reportHuman vaccines & immunotherapeutics2021

Predicting related factors of immunological response to hepatitis B vaccine in hemodialysis patients based on integration of decision tree classification and logistic regression.

Yongliang Feng, Jianmin Wang, Zhihong Shao, Zhuanzhuan Chen, Tian Yao, Shuang Dong, Yuanting Wu, Xiaohong Shi, Jing Shi, Guangming Liu and 9 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Yongliang FengSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Jianmin WangDepartment of Nephrology, Linfen Central Hospital, Shanxi, China.
Zhihong ShaoSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Zhuanzhuan ChenSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Tian YaoSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Shuang DongSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Yuanting WuSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Xiaohong ShiSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Jing ShiSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Guangming LiuClinical Laboratory, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China.
Jingen BaiDepartment of Nephrology, Lvliang People's Hospital, Lvliang, Shanxi, China.
Hongping GuoDepartment of Nephrology, Linfen People's Hospital, Linfen, Shanxi, China.
Hongting LiuDepartment of Nephrology, Yuncheng Central Hospital, Yuncheng, Shanxi, China.
Xiaofeng WuDepartment of Nephrology, The Second People's Hospital of Jinzhong, Jinzhong, Shanxi, China.
Liming LiuDepartment of Nephrology, Linfen Central Hospital, Shanxi, China.
Xiaohui SongDepartment of Nephrology, Fenyang Hospital of Shanxi Province, Fenyang, Shanxi, China.
Jiangtao ZhuDepartment of Nephrology, Changzhi Hospital of Traditional Chinese Medicine, Changzhi, Shanxi, China.
Suping WangSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Xiaofeng LiangChinese Preventive Medicine Association, Beijing, China.
Shanxi Medical University · CNChangzhi Medical College · CNXian Central Hospital · CNChinese Preventive Medicine Association · CNSecond People 's Hospital of Jinzhong · CNShanxi Fenyang Hospital · CNYuncheng University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The non/hypo-response rate of the hepatitis B vaccine among hemodialysis (HD) patients is still high, it is of great significance to explore the influencing factors and their relationships. To study the related factors and their relationships using logistic regression model and Chi-squared Automatic Interaction Detection (CHAID) decision tree model. A randomized controlled trial was conducted between February 2014 and May 2015 in China. HD patients being serologically negative for HBsAg and anti-HBs were randomly assigned to receive three intramuscular injections of the standard dose (20 µg) or high dose (60 µg) of recombinant hepatitis B vaccine at months 0, 1, and 6. Those with anti-HBs concentrations <100 mIU/mL, and ≥100 mIU/mL at month 7 were considered as non/hypo-response and high-level response, respectively. The non/hypo-response was 31.34% (89/284). After adjustment for confounders, logistic analysis showed that males (

Indexed as

Hepatitis BHepatitis B VaccinesDecision TreesHepatitis B AntibodiesHepatitis B Surface AntigensHumansLogistic ModelsMaleRenal DialysisHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesChi-squared automatic interaction detectionhemodialysisHepatitis B vaccinelogistic regression modelnon/hypo-response

Identifiers

PMID33989106
PMCPMC8381824
OpenAlexW3162677168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.