Trial reportNursing open2022
Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models.
Trial report in Nursing open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Effectiveness of Nurse-Led Interventions in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis.Journal of clinical nursing · 2026Pooled it
- Pooled it
- Primary-level and community worker interventions for the prevention of mental disorders and the promotion of well-being in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Effects of exercise interventions in Alzheimer's disease: A meta-analysis.Brain and behavior · 2023Pooled it
- Relieving care burden and promoting health-related quality of life for family caregivers of elderly people with Alzheimer's disease via an empowerment program.Aging clinical and experimental research · 2023Trial
- Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models.Nursing open · 2022Trial
- Therapeutic Effects of miR-29b-Enriched Nanovesicles on Mitochondrial Injury and Neuroinflammatory Processes in Alzheimer's Disease.Neurotoxicity research · 2026Article
- Estimating years of life lost due to premature mortality at regional level in France in 2017, using a probabilistic redistribution approach.BMC public health · 2025Article
- Models of Care for Older People: A Scoping Review.Journal of the American Geriatrics Society · 2025Article
- Effects of bifid triple viable capsules dissolving at intestines combined with emergency comprehensive nursing on intestinal microorganism and nutritional status of patients with coronary heart disease after percutaneous coronary intervention.Frontiers in medicine · 2025Article
- Article
- Comprehensive nursing intervention improves quality of life and reduces hospitalization time and expense in elderly patients with severe heart failure undergoing rh-BNP treatment.American journal of translational research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsWe conducted a multi-sectoral comprehensive intervention for elderly Alzheimer Disease patients and their caregivers to improve their quality of life.
designRandomized controlled trial.
methodsFrom June to June in 2019, 150 Alzheimer Disease patients were randomly selected from a nursing home in Zhejiang province of China, they were randomly divided into the intervention group and the control group. And they were given comprehensive and routine interventions respectively for six months. We used mixed models in our analyses to see how outcomes changed over time and how they were affected by the intervention, which could also solve the problems of missing values and data correlation.
resultsAfter six months, compared with the control group, the communication ability, housework handling ability, self-care ability and life quality of the patients in the intervention group were improved, and the quality of life and caring ability of their caregivers were also significantly improved.
conclusionThe multi-sectoral collaborative care model proposed in this study integrated resources from several departments, effectively improved the quality of life of patients and their caregivers, and provided a way of care services for patients with Alzheimer Disease. IMPACT: Multi-sectoral comprehensive intervention would improve the life quality of elderly patients with Alzheimer Disease and their caregivers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.