Evidence map›Paper›PMID 33988805›Full record

ArticleIrish journal of medical science2022

Assessing standards for prevention of early onset group B streptococcal (GBS) disease in Ireland.

Alex Dakin, Wendy Ferguson, Richard Drew, Naomi McCallion, Mary F Higgins, Maeve Eogan

Open access · hybridAbstract read
In one paragraph

Article in Irish journal of medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alex DakinObstetrics and Gynaecology, Rotunda Hospital, Dublin, Ireland.
Wendy FergusonPaediatrics, Rotunda Hospital, Dublin, Ireland.
Richard DrewMicrobiology, Dublin, Ireland.ORCID http://orcid.org/0000-0001-9797-3797
Naomi McCallionPaediatrics, Rotunda Hospital, Dublin, Ireland.
Mary F HigginsObstetrics and Gynaecology, National Maternity Hospital, Dublin, Ireland.ORCID http://orcid.org/0000-0002-6469-5169
Maeve EoganObstetrics and Gynaecology, Rotunda Hospital, Dublin, Ireland. meogan@rotunda.ie.ORCID http://orcid.org/0000-0002-5100-1981
Rotunda Hospital · IENational Maternity Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly onset group B streptococcal (GBS) disease can cause significant neonatal morbidity and mortality. There is currently no Irish national guideline for GBS screening, and protocols vary across maternity units. Polymerase chain reaction (PCR) testing at induction or labour onset informs triage for antibiotic prophylaxis; however, there are human and infrastructural resource requirements to enable widespread implementation.

aimOur aim was to identify current standard practices for GBS prevention in Irish obstetric and neonatal services and to utilise this data to inform the need for, and potential impact of implementation of, a national guideline.

methodsA questionnaire on GBS screening, management and existing resources was completed by an informed staff member from each of the 19 Irish maternity units, including questions regarding timing and method of screening, antibiotic usage, and neonatal management.

resultsOne unit (5.2%) performs routine GBS screening at 35-37 weeks of gestation. Twelve units (63%) screen for GBS following spontaneous rupture of membranes (SROM) after 37 weeks, of which two (17%) perform PCR and ten (83%) culture testing. Seventeen units (89.3%) have access to a GeneXpert PCR machine, and of these, two (11.7%) use the machine for rapid GBS testing. Two units screen patients for GBS at either the start of labour or induction of labour. Four units (21%) use the neonatal early onset sepsis (EOS) calculator. Sixteen units (84%) do not treat asymptomatic infants born to GBS-positive mothers.  

conclusionThere is a lack of consistency in the methods for GBS screening and disease prevention across the country, highlighting the need for a national guideline accompanied by an implementation plan and budget to standardise care.

Indexed as

Pregnancy Complications, InfectiousStreptococcal InfectionsAntibiotic ProphylaxisFemaleHumansInfantInfant, NewbornIrelandPregnancyStreptococcus agalactiaeGroup B streptococcusIntrapartum antibiotic prophylaxisPolymerase chain reactionScreening

Identifiers

PMID33988805
PMCPMC8120250
OpenAlexW3162859505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.