SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Medicinal plants used for the treatment of mucositis induced by oncotherapy: a systematic review.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Pooled it
- Effect of Chamomile on the Complications of Cancer: A Systematic Review.Integrative cancer therapiesPooled it
- Oral mucositis management with photobiomodulation, Bidens pilosa L. (Asteraceae) and Curcuma longa L. (Zingiberaceae), the FITOPROT herbal medicine, and its influence on inflammatory cytokine levels: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- Effects of a mucoadhesive phytomedicine (Curcuma longa L. and Bidens pilosa L.) on radiotherapy-induced oral mucositis and quality of life of patients undergoing head and neck cancer treatment: randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- Article
- Herbal Products and Dietary Supplements in Radiation Oncology: Evidence, Safety, and Practical Patient Counseling.Seminars in radiation oncology · 2026Review
- SmartGel OV: A NaturalMedicina (Kaunas, Lithuania) · 2025Observational
- The healing effect of nano emulsified Plantago major L extract on oral wounds in a wistar rat model.BMC complementary medicine and therapies · 2024Article
- Importance of phytotherapy for oral health care and quality of life in adults: A scoping review.Journal of dental sciences · 2024Article
- Thymus satureioides Coss. combats oral ulcer via inhibition of inflammation, proteolysis, and apoptosis.Inflammopharmacology · 2023Article
- Letter to the editor: Re: Re: "Medicinal plants used for the treatment of mucositis induced by oncotherapy: a systematic review" by Eubank et al.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Letter to the editor: Re: "Medicinal plants used for the treatment of mucositis induced by oncotherapy: a systematic review" by Eubank et al.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Chemotherapy-associated oral microbiome changes in breast cancer patients.Frontiers in oncology · 2022Article
- Antimicrobial potential of plant extracts from the Brazilian Cerrado.Brazilian dental journalArticle
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis systematic review aimed to identify effective medicinal plants for the treatment of mucositis induced by oncotherapy.
methodsThe clinical question was the following: "Which medicinal plants are effective in the treatment of oral mucositis induced by cancer treatment?" (PubMed, Medline, Web of Science, Scopus, Lilacs, and SciELO). The keywords were the following: phytotherapy OR "herbal drug" OR "plant extract" OR plant OR "medicinal plant" OR pharmacognosy OR ethnobotany OR ethnomedicine OR ethnopharmacology OR "flower essences" OR "natural product" AND mucositis OR mucositides OR stomatitis OR stomatitides OR "oral ulcer" AND chemotherapy OR radiotherapy OR immunotherapy OR cancer OR neoplasm OR neoplasm OR tumor OR tumor. The inclusion criteria for the selection of articles were the type of study design (clinical trials) and the studied population (cancer patients presenting lesions of oral mucositis having undergone treatment with medicinal plants).
resultsAfter evaluation of the works, 24 of 893 articles were selected. Matricaria chamomilla (chamomilla) presented promising results, such as a reduction in severity and lesion incidence with improved pain symptomatology. The plant extracts Isatis indigótica, Olea europaea, Calendula officinalis, A. digitatae, and M. sylvestris improved the lesions. Mucotrol™ and QRLYD herbal products improved the degree of severity of the lesions, while SAMITAL® and MUCOSYTE allowed for greater pain control.
conclusionThe complementary treatment of oral mucositis in cancer patients, with analgesic and anti-inflammatory actions with lower side effects, is an alternative for healthcare professionals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.