Evidence map›Paper›PMID 33988169›Full record

ArticleActa bio-medica : Atenei Parmensis2021

A real world investigation on prevalence, clinical features, and therapy of inflammatory bowel disease in the city of Messina, Italy.

Alessandra Belvedere, Riccardo Scoglio, Anna Viola, Giuseppe Costantino, Aldo Sitibondo, Marco Muscianisi, Santi Inferrera, Angela Alibrandi, Walter Fries

Abstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. VISCERAL SENSITIVITY INDEX (VSI-IT): Italian Adaptation and Validation.European journal of investigation in health, psychology and education · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandra BelvedereClinical Unit for Chronic Bowel Disorders, Dept. of Clinical and Experimental Medicine, University of Messina, Messina; Italy. alessandra-belvedere@virgilio.it.
Riccardo ScoglioItalian Society of General Medicine (SIMG); Section Messina, Messina; Italy. riccardoscoglio@virgilio.it.
Anna Violaa:1:{s:5:"en_US";s:109:"Clinical Unit for Chronic Bowel Disorders, Dept. of Clinical and Experimental Medicine, University of Messina";}. annaviola88@gmail.com.
Giuseppe CostantinoClinical Unit for Chronic Bowel Disorders, Dept. of Clinical and Experimental Medicine, University of Messina, Messina; Italy. giu.costantin@gmail.com.
Aldo SitibondoClinical Unit for Chronic Bowel Disorders, Dept. of Clinical and Experimental Medicine, University of Messina, Messina; Italy. aldo.sitibondo@gmail.com.
Marco MuscianisiClinical Unit for Chronic Bowel Disorders, Dept. of Clinical and Experimental Medicine, University of Messina. marcom1987@gmail.com.
Santi InferreraItalian Society of General Medicine (SIMG); Section Messina, Messina; Italy. inferrera@gmail.com.
Angela AlibrandiDepartment of Economics, University of Messina, Messina; Italy. aalibrandi@unime.it.
Walter FriesClinical Unit for Chronic Bowel Disorders, Dept. of Clinical and Experimental Medicine, University of Messina. fwalter@unime.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe absence of a national register of inflammatory bowel diseases (IBD) hinders effective health care planning in Italy.

aimsto investigate prevalence of IBD in the city of Messina, Italy, based on General Practitioner (GP) records, and to establish current treatments prescribed by different health care providers.

methodsdata were extracted from GP databases with the help of disease-specific healthcare cost exemption codes combined with ICD9 codes for ulcerative colitis (UC) and Crohn's disease (CD), and prescription for mesalazine. Disease and treatment-related data were collected together with information on employment status and the current healthcare provider.

resultsEighty-six GPs participated covering a population of 100,834 people. IBD prevalence (419/105) was 80% higher than estimates of the Regional Health Authorities. Incidence showed a seven-fold increase over the past 30 years. Only 51% of CD and 26% of UC patients were followed by a dedicated IBD centre with more frequent prescriptions of immunomodulators and biologics (p<0.001) compared to GPs.

conclusionsReal world data show much higher figures on IBD prevalence than administrative estimates. Differences in therapeutic approaches between IBD-specialists and non-specialists may reflect poor confidence in managing immunosuppressive therapies by the latter, but may lead to inadequate therapy and cancer surveillance.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesHumansItalyPrevalence

Identifiers

PMID33988169
PMCPMC8182597

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.