Evidence map›Paper›PMID 33988123›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2021

Unprecedented increase of West Nile virus neuroinvasive disease, Spain, summer 2020.

Lucía García San Miguel Rodríguez-Alarcón, Beatriz Fernández-Martínez, María José Sierra Moros, Ana Vázquez, Paula Julián Pachés, Elena García Villacieros, María Belén Gómez Martín, Jordi Figuerola Borras, Nicola Lorusso, Julian Mauro Ramos Aceitero and 11 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. Ecotypes,bioRxiv : the preprint server for biology · 2026
    Article
  3. Predicting West Nile virus circulation: a 20-year spatiotemporal study in humans and animals in Spain, 2003 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Long-Term Surveillance ofMicroorganisms · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. New enemies: contribution of CPathogens and global health · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 2 countries.

Lucía García San Miguel Rodríguez-AlarcónMinistry of Health, Coordinating Center of Health Alerts and Emergencies, Madrid, Spain.
Beatriz Fernández-MartínezNational Center for Epidemiology, Instituto de Salud Carlos III, Ministry of Science and Innovation, , Madrid, Spain.
María José Sierra MorosMinistry of Health, Coordinating Center of Health Alerts and Emergencies, Madrid, Spain.
Ana VázquezCIBER Epidemiology and Public Health, Madrid, Spain.
Paula Julián PachésConsorcio Hospital General de Valencia, Valencia, Spain.
Elena García VillacierosMinisterio de Agricultura, Pesca y Alimentación, Dirección General de Sanidad de la Producción Agraria, Madrid, Spain.
María Belén Gómez MartínMinisterio de Agricultura, Pesca y Alimentación, Dirección General de Sanidad de la Producción Agraria, Madrid, Spain.
Jordi Figuerola BorrasCIBER Epidemiology and Public Health, Madrid, Spain.
Nicola LorussoJunta de Andalucía, Servicio de Vigilancia y Salud laboral Seville, Spain.
Julian Mauro Ramos AceiteroJunta de Extremadura, Subdireccion de Epidemiologia, Mérida-Badajoz, Spain.
Elena MoroMinistry of Health, Scientific Committee on Transfusion Safety, Madrid, Spain.
Aránzazu de CelisMinistry of Health, Scientific Committee on Transfusion Safety, Madrid, Spain.
Salvador OyonarteMinistry of Health, Scientific Committee on Transfusion Safety, Madrid, Spain.
Beatriz MahilloOrganización Nacional de Trasplantes Madrid, Spain.
Luis José Romero GonzálezMinisterio de Agricultura, Pesca y Alimentación, Dirección General de Sanidad de la Producción Agraria, Madrid, Spain.
María Paz Sánchez-SecoNational Microbiology Center, Instituto de Salud Carlos III, Ministry of Science and Innovation.
Berta Suárez RodríguezMinistry of Health, Coordinating Center of Health Alerts and Emergencies, Madrid, Spain.
Ulises Ameyugo CatalánJunta de Andalucía. Consejería de Salud y Familias. Dirección General de Salud Pública y Ordenación Farmacéutica. Subdirección de Protección de la Salud, Seville, Spain.
Santiago Ruiz ContrerasDiputación de Hueva. Servicio de Control de Mosquitos, Huelva, Spain.
Mayte Pérez-OlmedaNational Microbiology Center, Instituto de Salud Carlos III, Ministry of Science and Innovation.
Fernando Simón SoriaMinistry of Health, Coordinating Center of Health Alerts and Emergencies, Madrid, Spain.
Ministry of Health · ESMinisterio de Agricultura, Pesca y Alimentación · ESCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESInstituto de Salud Carlos III · ESJunta de Andalucía · ESGovernment of Extremadura · ESHospital General Universitario De Valencia · ESMinistry of Science · MEOrganización Nacional de Trasplantes · ESUniversidad de Huelva · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cases of West Nile neuroinvasive disease (WNND) in Spain increased in summer 2020. Here we report on this increase and the local, regional and national public health measures taken in response. We analysed data from regional surveillance networks and the National Epidemiological Surveillance Network, both for human and animal West Nile virus (WNV) infection. During the 2020 season, a total of 77 human cases of WNV infection (median age 65 years; 60% males) were detected in the south-west of Spain; 72 (94%) of these cases developed WNND, presenting as meningoencephalitis, seven of which were fatal. In the previous two decades, only six human cases of WNND were detected in Spain. Reduced activities for vector control this season, together with other factors, might have contributed to the massive increase. Public health measures including vector control, campaigns to raise awareness among physicians and the general population, and interventions to ensure the safety of donations of blood products, organs, cells and tissues were effective to reduce transmission. Going forward, maintenance of vector control activities and an update of the vector-borne diseases response plan in Spain is needed.

Indexed as

MeningoencephalitisWest Nile FeverWest Nile virusAgedAnimalsFemaleHumansMaleSeasonsSpainepidemiologySpainsurveillancevector-borne infectionsviral infectionsWest Nile feverWest Nile virusWNV

Identifiers

PMID33988123
PMCPMC8120797
OpenAlexW3163578487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.